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Kell alloimmünizasyonuna bağlı hidrops fetalis: olgu sunumu

Hydrops fetalis due to Kell alloimmunization: a case report

Journal Name:

  • Gülhane Tıp Dergisi

Publication Year:

  • 2011

Key Words:

Keywords (Original Language):

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Abstract (2. Language): 
Kell alloimmunization is one of the rare but at the same time most frequent causes of hemolytic disease of fetus and newborn after anti-D alloimmunization. Management of Kell alloimmunization which uniquely demonstrates its effect via the supression of fetal erythropoietic response is somewhat different from alloimmunization occuring due to RhD antibodies. In this case report fetal and neonatal hemolytic disease occuring due to Kell izoimmunization is discussed under the light of literature knowledge regarding a case of hydrops fetalis developing due to sensitization with anti-Kell antibodies and resulting in utero excitus despite intensive follow-up and treatment.
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Abstract (Original Language): 
Kell alloimmünizasyonu, fetal ve yenidoğan hemolitik hastalığının anti-D alloimmünizasyonundan sonra en sık izlenen, fakat aynı zamanda nadir rastlanılan nedenlerinden birisidir. Kendine has özelliği ile fetal eritropoetik cevabın baskılanması üzerinden etki eden Kell alloimmünizasyonunun yönetimi RhD antikorları ile oluşan alloimmünizasyondan biraz farklıdır. Bu yazıda anti-Kell antikorları ile sensitizasyon sonucunda oluşan hidrops fetalis ve yoğun tedavi-takibe rağmen in-utero eksitus ile sonuçlanan bir olgu nedeni ile Kell izoimmünizasyonuna bağlı olarak oluşan fetal ve yenidoğan hemolitik hastalığı mevcut literatür bilgisi ışığında tartışılmıştır.
FULL TEXT (PDF): 
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  • 3
219-222
  • Turkish

REFERENCES

References: 

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