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HEAVY METAL INDUCED ENZYM E RESPONSE IN TILAPIA MOSSAMBICUS

Journal Name:

  • The International Journal of Pharmaceutical Research and Bio-Science

Publication Year:

  • 2012

Key Words:

Author NameUniversity of Author
Abstract (2. Language): 
Copper and cadmium is a trace element which is essential to the function of specific proteins and enzymes. However, at high concentrations it may be toxic to organisms. The aim of the present study was to evaluate the fish adaptative response to experimental copper and cadmium pollution by biochemical methods, the enzymatic variations simultaneously appeared after acute copper and cadmium exposure. We studied effects of two essential and toxic metals (Cu and Cd) on enzymatic characteristics of the fish Tilapia mossambicus using environmentally relevant concentrations. Fish were exposed to metal through seawater for 24, 48,72and 96 hrs. Estimate the toxicity of cadmium and copper to fingerlings of Tilapia mossambicus as well as the effect of different concentrations of Cd and Cu on some enzymatic studies (Superoxide dis mutase, Catalase, Lactate dehydrogenase, glutathione-S-transferase, Protease, Amylase, lipase) in the fish. 96-h LC50s of Cu and Cd were 6.1 and 4.9 ppm, respectively. Levels of enzymes were increased within 2 days of exposure to muscle tissue. Activities of antioxidant and digestive enzymes such, Superoxide dismutase, Catalase, Lactate dehydrogenase, glutathione-S-transferase, were altered in exposed fish. The present study showed high toxicity of cadmium to fish Tilapia mossambicus comparing to copper.
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  • English

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