1. American Academy of Pediatrics Committee on Infectious Diseases. Reduction of the
influenza burden in children. Pediatrics 2002; 110 (6): 1246-1252.
2. American Academy of Pediatrics. Influenza. In: Pickering LK (ed). Red Book: 2009
American Academy of Pediatrics Report of the Committee on Infectious Diseases.
American Academy of Pediatrics. Elk Grove Village, IL, 27 ed. 2009; pp 400-411.
3. Burroughs M, Horga MA, Murrel MT, Moscona A. Respiratory infections. In: Gershon
AA, Hotes PJ, Katz SL (eds). Krugman’s Infectious Diseases of Children. Mosby Co, St
Louis, 11th ed. 2006; pp 493-529.
4. CDC. Seasonal Influenza (Flu) - Weekly Report Influenza Summary Update. http://
www.cdc.gov/flu/weekly/
5. CDC. 2009 H1N1 Early Outbreak and Disease Characteristics. http://www.cdc.gov/
h1n1flu/surveillanceqa.htm
24
Tablo 2. Çocuklarda influenza infeksiyonlarının tedavi ve profilaksisinde kullanılan
antiviral ilaçlar, doz ve süreleri.
Etken Madde Tedavi Dozu Profilaksi Dozu
Oseltamivir
15 kg veya altı 60 mg günde 2 doza bölünerek verilecek 30 mg günde bir kez
15-23 kg 90 mg günde 2 doza bölünerek verilecek 45 mg günde bir kez
24-40 kg 120 mg günde 2 doza bölünerek verilecek günde bir kez
> 40 kg 150 mg günde 2 doza bölünerek verilecek 75 mg günde bir kez
Zanamivir 2 defa 5 mg inhaler (toplam 10 mg) (7 yaş üzerindekiler 2 defa
günde 2 kez 5 mg inhaler (toplam 10 mg)
günde 1 kez
6. Ciblak MA, AlbayrakN, OdabasY, Basak Altas A, Kanturvardar M, Hakoksuz M, Sucakli
B, Korukluoglu G, Bal E, Ertek M, Badur S. Cases of influenza A (H1N1)v reported in
Turkey, May-July 2009. Eurosurveillance 2009; 14 (32): pii=19304.
7. Garten RJ, Davis CT, Russell CA, Shu B, Lindstrom S, Balish A, Sessions WM, Xu X,
Skepner E, Deyde V, Okomo-Adhiambo M, Gubareva L, Barnes J, Smith CB, Emery SL,
Hillman MJ, Rivailler P, Smagala J, de Graaf M, Burke DF, Fouchier RA, Pappas C,
Alpuche-Aranda CM, López-Gatell H, Olivera H, López I, Myers CA, Faix D, Blair PJ, Yu
C, Keene KM, Dotson PD Jr, Boxrud D, Sambol AR, Abid SH, St George K, Bannerman
T, Moore AL, Stringer DJ, Blevins P, Demmler-Harrison GJ, Ginsberg M, Kriner P,
Waterman S, Smole S, Guevara HF, Belongia EA, Clark PA, Beatrice ST, Donis R, Katz J,
Finelli L, Bridges CB, Shaw M, Jernigan DB, Uyeki TM, Smith DJ, Klimov AI, Cox NJ.
Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses
circulating in humans. Science 2009; 325 (5937): 197-201.
8. Hackett S, Hill L, Patel J, Ratnaraja N, Ifeyinwa A, Farooqi M, Nusgen U, Debenham P,
Gandhi D, Makwana N, Smit E, Welch S. Clinical characteristics of paediatric H1N1
admissions in Birmingham, UK. Lancet 2009; 374 (9690): 605.
9. http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPa...
Providers/ucm183870.htm
10. Kimberlin D. Oseltamivir (OST) and OST carboxylate (CBX) pharmacokinetics (PK) in
infants: Interim results from a multicenter trial. Abstract accepted to Infectious Diseases
Society of America Meeting, October 2009.
11. Kwong KL, Lung D, Wong SN, Que TL, Kwong NS. Influenza-related hospitalisations in
children. J Paediatr Child Health 2009; 45: 660-664.
12. La Ruche G, Tarantola A, Barboza P, Vaillant L, Gueguen J, Gastellu-Etchegorry M,
the epidemic intelligence team at InVS. The 2009 pandemic H1N1 influenza and
indigenous populations of the Americas and the Pacific. Euro Surveill 2009; 14 (42):
pii=19366.
13. Libster R, Bugna J, Coviello S, Hijano DR, Dunaiewsky M, Reynoso N, Cavalieri ML,
Guglielmo MC, Areso MS, Gilligan T, Santucho F, Cabral G, Gregorio GL, Moreno R, Lutz
MI, Panigasi AL, Saligari L, Caballero MT, Egües Almeida RM, Gutierrez Meyer ME,
Neder MD, Davenport MC, Del Valle MP, Santidrian VS, Mosca G, Garcia Domínguez M,
Alvarez L, Landa P, Pota A, Boloñati N, Dalamon R, Sanchez Mercol VI, Espinoza M,
Peuchot JC, Karolinski A, Bruno M, Borsa A, Ferrero F, Bonina A, Ramonet M, Albano
LC, Luedicke N, Alterman E, Savy V, Baumeister E, Chappell JD, Edwards KM, Melendi
GA, Polack FP. Pediatric Hospitalizations Associated with 2009 Pandemic Influenza A
(H1N1) in Argentina. N Engl J Med 2009; 362:45-55.
14. Louie JK, Acosta M, Winter K, Louie JK, Acosta M, Winter K, Jean C, Gavali S, Schechter
R, Vugia D, Harriman K, Matyas B, Glaser CA, Samuel MC, Rosenberg J, Talarico J, Hatch
D; California Pandemic (H1N1) Working Group. Factors associated with death or
25
hospitalization due to pandemic 2009 influenza A(H1N1) infection in California. JAMA
2009; 302: 1896-1902.
15. Meissner HC. Antiviral drugs for prophylaxis and treatment of influenza. Pediatr Infect Dis
J 2001; 20 (12): 1165-1167.
16. Newland JG, Laurich VM, Rosenquist AW, Heydon K, Licht DJ, Keren R, Zaoutis TE,
Watson B, Hodinka RL, Coffin SE. Neurologic complications in children hospitalized with
influenza: characteristics, incidence, and risk factors. J Pediatr 2007; 150: 306-310.
17. Outbreak of swine-origin influenza A (H1N1) virus infection-Mexico, March-April 2009.
MMWR Morb Mortal Wkly Rep 2009; 58: 467.
18. Perez-Padilla R, de la Rosa-Zamboni D, Ponce de Leon S, Hernandez M, Quiñones-Falconi
F, Bautista E, Ramirez-Venegas A, Rojas-Serrano J, Ormsby CE, Corrales A, Higuera A,
Mondragon E, Cordova-Villalobos JA; INER Working Group on Influenza. Pneumonia
and respiratory failure from swine-origin influenza A (H1N1) in Mexico. N Engl J Med
2009; 361: 680-689.
19. Quach C, Piche-Walker L, Platt R, Moore D. Risk factors associated with severe influenza
infections in childhood. Implication for vaccine strategy. Pediatrics 2003; 112: e197-201.
20. RelloJ, Rodriguez A, Ibanez P, Socias L, Cebrian J, Marques A, Guerrero J, Ruiz-Santana
S, Marquez E, Del Nogal-Saez F, Alvarez-Lerma F, Martínez S, Ferrer M, Avellanas M,
Granada R, Maraví-Poma E, Albert P, Sierra R, Vidaur L, Ortiz P, Prieto del Portillo I,
Galván B, León-Gil C; H1N1 SEMICYUC Working Group. Intensive care adult patients
with severe respiratory failure caused by Influenza A (H1N1)v in Spain. Critical Care 2009;
13 (5): R148. Epub 2009 Sep 11.
21. Sağlık Bakanlığı. Pandemik (H1N1) 2009 Gribi Klinik Vaka Yönetimi.
http://www.grip.gov.tr/index.php?option=com_content&view=article&id=666:...
mi&catid=102:rehber-ve-prosueduerler&Itemid=514
22. Shun-Shin M, Thompson M, Heneghan C, Perera R, Harnden A, Mant D. Neuraminidase
inhibitors for treatment and prophylaxis of influenza in children: systematic review and
meta-analysis of randomised controlled trials. BMJ. 2009; 10:339.
23. Tsolia MN, Logotheti I, Papadopulos NG, Mavrikou M, Spyridis NP, Drossatou P, Kafetzis
D, Konstantopoulos A; Outpatient Flu Study Group. Impact of influenza infection in healthy
children examined as outpatients and their families. Vaccine 2006; 14: 5970-5976.
24. Vincent A, Wenjun M, Lager MK, Janke B, Richt J. Swine influenza viruses: A North
American perspective. Advances in Virus Research 2008; 72: 127-154.
25. World Health Organization. World now at the start of 2009 influenza pandemic.
http://www.who.int/mediacentre/news/statements/2009/h1n1_pandemic_phase6...
/en/index.html (Accessed June 18, 2009)
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