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Collagenous Fibroma (Desmoplastic Fibroblastoma): Different Localization. A Case Report

Kollajenöz Fibrom ( Desmoplastik Fibroblastom): Farklı Bir Lokalizasyon. Olgu Sunumu

Journal Name:

  • İnönü Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 2007

Key Words:

Keywords (Original Language):

Author Name
Abstract (2. Language): 
Collagenous fibroma is an extremely rare benign soft tissue tumor which arises in the subcutaneous tissue or muscle. We report a rare case of a collagenous fibroma in a 44-year-old woman who presented with a mass in the anterior chest wall. Microscopically, the tumor was hypocellular and consisted of diffuse bland spindle to stellate – shaped cells embedded in a collagenous stroma. Immunohistochemically, the tumor cells were diffusely and strongly positive for vimentin. Some cells contained alpha smooth muscle actin. They were uniformly negative for S-100 protein and CD34. After surgical excision, no recurrence or metastasis was observed during a 6 month follow-up period. A discussion of the histopathological features and a review of the literature is given.
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Abstract (Original Language): 
Kollajenöz fibrom kas veya subkutan dokuda gelişen çok nadir bir yumuşak doku tümörüdür. Bu makalede göğüs ön duvarında kitle şikayetiyle başvuran ve kollajenöz fibrom tanısı alan 44 yaşındaki olguyu sunmayı amaçladık. Mikroskopik olarak hiposellüler tümör, kollajenöz stroma içerisinde yerleşmiş atipi göstermeyen iğsi ve yıldızsı şekilli hücrelerden oluşmakta idi. İmmunohistokimyasal olarak tümöral hücreler vimentin ile yaygın ve kuvvetli pozitif, alfa düz kas aktini ile ise fokal pozitifti. S-100 ve CD34 boyaları ise negatif idi. Lezyonun cerrahi ekzisyonundan sonraki 6 aylık izlem döneminde rekürrens veya metastaz izlenmedi. Tümörün histopatolojik özellikleri literatürler eşliğinde tartışıldı.
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  • 3
181-184
  • Turkish

REFERENCES

References: 

1. Evans HL. Desmoplastic fibroblastoma. A report of seven cases. Am J Surg Pathol.
1995 Sep;19(9):1077-81.
2. Nielsen GP, O'Connell JX, Dickersin GR, Rosenberg AE. Collagenous fibroma
(desmoplastic fibroblastoma): a report of seven cases. Mod Pathol. 1996 Jul;9(7):781-
5.
3. Hasegawa T, Shimoda T, Hirohashi S, et al. Collagenous fibroma (desmoplastic
fibroblastoma): report of four cases and review of the literature.
Arch Pathol Lab Med. 1998 May;122(5):455-60. Review.
Çallı et al
184
4. Jang JG, Jung HH, Suh KS, Kim ST. Desmoplastic fibroblastoma (collagenous
fibroma). Am J Dermatopathol. 1999 Jun;21(3):256-8.
5. Weisberg NK, DiCaudo DJ, Meland NB. Collagenous fibroma (desmoplastic
fibroblastoma). J Am Acad Dermatol. 1999 Aug;41(2 Pt 2):292-4.
6. Junkins-Hopkins JM, Johnson WC. Desmoplastic fibroblastoma. J Cutan Pathol.
1998 Sep;25(8):450-4.
7. Miettinen M, Fetsch JF. Collagenous fibroma (desmoplastic fibroblastoma): a
clinicopathologic analysis of 63 cases of a distinctive soft tissue lesion with stellateshaped
fibroblasts. Hum Pathol. 1998 Jul;29(7):676-82.
8. Ide, F. et al. Collagenous fibroma (desmoplastic fibroblastoma) presenting as a
parotid mass. J Oral Pathol Med 1999; 28:465-8.
9. Mesquita, R. A. et al. Collagenous fibroma (desmoplastic fibroblastoma) of the palate:
a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001; 91: 80-4.
10. Shimoyama T, Horie N, Ide F. Collagenous fibroma (desmoplastic fibroblastoma): a
new case originating in the palate. Dentomaxillofac Radiol. 2005 Mar;34(2):117-9
11. Hao S, Cherian R, Templeton KJ, et al. Collagenous fibroma (desmoplastic
fibroblastoma) of pectoralis minor muscle. Orthopedics. 2003 Dec;26(12):1227-8.
12. Allen PW. Selected case from the Arkadi M. Rywlin International Pathology Slide
Seminar: desmoplastic fibroblastoma (collagenous fibroma). Adv Anat Pathol. 2001
Jan;8(1):23-6.
13. Fetsch CF, Montgomery EA, Meis JM. Calcifiying fibrous pseudotumor. Am J Surg
Pathol 1993;17:502-8.
14. Westra WH, Gerald WL, Rosai J. Solitary fibrous tumor. Consistent CD34
immunoreactivity and occurrence in the orbit. Am J Surg Pathol 1994;18:1992.
15. Huang HY, Sung MT, Eng HL, et al. Superficial collagenous fibroma:
immunohistochemical, ultrastructural, and flow cytometric study of three cases,
including one pemphigus vulgaris patient with a dermal mass. Apmis 2002;
110(4):283-9.
16. Sciot R. et al. Collagenous fibroma (desmoplastic fibroblastoma): genetic link with
fibroma of tendon sheath? Mod Pathol. 1999;12:565-8.

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