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Karpal Tünel Sendromunun Tedavisinde İyontoforez, Lokal Kortikosteroid Enjeksiyon ve Non-Steroid Anti-İnflamatuar İlaç Etkinliğinin Karşılaştırılması

Comparison of the Effects of Iontophoresıs, Local Corticosteroid Injection and Non-Steroid Anti-inflammatory Drug in the Treatment of Carpal Tunnel Syndrome

Journal Name:

  • Fırat Tıp Dergisi

Publication Year:

  • 2008

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Abstract (2. Language): 
Objective: The aim of this study was to compare the efficacy of iontophoresis, corticosteroid injection and non-steroid anti-inflammatory (NSAID) drug on symptoms, grip strength and hand function in patients with CTS. Materials and Methods: Forty-eight patients with moderate CTS were recruited and divided into three groups. The patients were treated with iontophoresis in-group A, with injections in-group B, with NSAIDs in-group C. All of the patients were given wrist splints in neutral position. BSSS (Boston Symptom Severity Scale) was used to evaluate the symptoms, grip strength was detected by Jamar hand dynamometer, lateral, palmar and tip pinch strength were measured by a pinchmeter and hand function was recorded by Nine Hole Peg Test (NHPT). The patients were evaluated before treatment, at the 1st and the 3rd month after treatment. Results: The BSSS scores improved in all groups at the 1st month (p<0.001), in groups A and B (p<0.001) and in group C (p<0.01) at the 3rd month. The lateral pinch strength of the patients' in-group A and the palmar pinch of the patients' in-group B were improved at 3rd month (respectively p<0.01, p<0.05). There was no difference in the groups regarding to grip strength and NHPT at the 1st and 3rd months. Conclusion: Ionthophoresis, injection and NSAII drug demonstrated no superior results. All methods make an improvement in the symptoms. Iontophoresis and injection may improve grip strength. Using night splints alone can be effective in the symptoms, lateral and palmar strength. ©2008,Firat University, Medical Faculty
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Abstract (Original Language): 
Amaç: Primer KTS'li hastalarda steroid iyontoforezi, lokal kortikosteroid enjeksiyonu ve non-steroid anti-inflamatuar ilacın (NSAII) semptom, kavrama gücü ve el fonksiyonu üzerine olan etkilerini karşılaştırmaktı. Gereç ve Yöntem: Orta düzeyde KTS tanısı olan 48 hasta alındı ve 3 gruba ayrıldı. Grup A'ya (n=16), steroid iyontoforezi, grup B'ye (n=18) lokal kortikosteroid enjeksiyonu, grup C'ye (n=14) NSAII tedavisi uygulandı. Hastaların tümüne el el-bileğini nötral pozisyonda tutan istirahat splinti verildi. Hastaların semptomları Boston Semptom Ciddiyet Ölçeği (BSCÖ); kavrama güçleri Jamar el dinanometresi; lateral, palmar ve parmak ucu kavrama güçleri pinçmetre, el fonksiyonları Nine Hole Peg Test (NHPT) ile tedavi öncesi, tedaviden 1 ve 3 ay sonra değerlendirildi. Bulgular: BSCÖ'de 1. ay sonunda tüm tedavi gruplarında (p<0.001), 3. ay sonunda grup A, B'de (p<0.001), ve grup C'de (p<0.01) anlamlı düzelme saptandı. Grup A'da lateral kavrama güçlerinde; grup B'de ise palmar kavrama güçlerinde 3. ayda anlamlı iyileşme tespit edildi (sırasıyla p<0,01, p<0.05). Tüm gruplarda kavrama güçleri ve NHPT tedavinin 1. ve 3. ay sonunda farklılık göstermedi (p>0.05). Sonuç: KTS tedavisinde iyontoforez, steroid enjeksiyonu ve NSAII kullanımının birbirlerine üstünlüklerinin olmadığı belirlenmiştir. Her üç yöntemde hastaların semptomlarında düzelme sağlamaktadır. İyontoforez ve steroid enjeksiyonu kavrama güçlerinin iyileşmesini etkileyebilmektedir. Tek başına splint kullanımının da hastaların semptomları, lateral ve palmar kavrama güçleri üzerine etkili olabileceği düşünülmüştür. 2008, Fırat Üniversitesi, Tıp Fakültesi
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