Journal Name:
- The International Journal of Pharmaceutical Research and Bio-Science
Key Words:
Abstract (2. Language):
Aim
skin and soft tissue infections. The resistance to antimicrobial agent among
staphylococci is an increasing problem. Clindamycin is considered to be one of the
alternative agents in
clindamycin resistance among
demonstrates a simple and reliable method
of 300
specimens like pus, blood, sputum, throat swab, ear swab, high vaginal swab, CSF,
urine, pleural fluid, semen, bile, corneal swab, etc. To detect inducible clindamycin
resistance, 15 μg erythromycin and 2 μg clindamycin
Hinton agar plate at a distance of 15 mm apart (measuring edge to edge). If there is
inducible clindamycin resistance, the erythromycin will diffuse through the agar and
resistance to clindamycin will be induced, resulting flatt
inhibition adjacent to erythromycin disc and giving D
of 300 Staphylococcus aureus isolates, 109 strains (36.33%) were found to be MRSA
and 191 strains (63.67%) were Non MRSA. Of these, 90 strains (30%)
be resistance to erythromycin. These isolates were subjected to D tests shows 11
isolates resistance to both erythromycin and clindamycin indicating constitutive MLS phenotype and
isolates, 47 isolates showed positive D- Test indicating. out of these 79 isolates showed positive D- TEST indicating inducible MLSB phenotype while 32 gave negative D test indicating MS phenothpe.
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