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Yetişkin Nefrotik Sendromun İlk Bulgusu Olarak Portal Ven Trombozu ile İlişkili Trombositopeni: Olgu Sunumu

Thrombocytopenia Associated with Portal Vein Thrombosis as a Presenting Sign of Adult Nephrotic Syndrome: A Case Report

Journal Name:

  • Türk Nefroloji, Diyaliz ve Transplantasyon Dergisi

Publication Year:

  • 2014
DOI: 
10.5262/tndt.2014.1001.15

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
The nephrotic syndrome is a risk factor for venous thromboembolism. This is strikingly apparent in young adults. Portal vein thrombosis as an initial sign of nephrotic syndrome is extremely rare. A 49-year-old male was admitted to our center with complaints of severe abdominal distension, generalized edema, and oliguria for one week. On admission, serum creatinine was 2.1 mg/dl, proteinuria was 3.2 g/ dl, serum albumin was 1.8 g/dl, and platelet count was 13.000/ml. Microscopic hematuria, acute kidney injury, and nephrotic range proteinuria were present. Portal vein thrombosis, massive ascites, and mild splenomegaly were detected by Doppler ultrasound and dynamic magnetic resonance imaging. We present here a case with rapidly progressive glomerulonephritis who developed acute portal vein thrombosis.
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Abstract (Original Language): 
Nefrotik sendrom venöz tromboembolizm gelişimi açısından bir risk faktörüdür. Daha çok genç hastalarda görülmesi ilgi çekicidir. Portal ven trombozunun nefrotik sendrom başlangıç bulgusu olarak ortaya çıkması oldukça nadirdir. 49 yaşında erkek hasta kliniğimize 1 haftadır karında şişkinlik hissi, yaygın ödem ve idrar çıkımında azalma nedeniyle kabul edildi. Hastaneye yatışı esnasında serum creatinin 2,1 mg/dl, proteinuria 3,2 g/dl, serum albümin 1,8 g/dl, ve trombosit sayısı 13.000/ml idi. Mikroscopik hematuri ve nefrotik düzeyde proteinüri mevcuttu. Doppler ultrasound ve dinamik magnetik resonans görüntülemesinde portal ven thrombozu, yaygın assit ve orta derecede splenomegali tespit edildi. Bu olguda biz, hızlı ilerleyen progresif glomerülonefritin başlangıç bulgusu olarak portal ven trombozunu yayınlamayı amaçladık.
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REFERENCES

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