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Çocuk Hastada IgA Nefropatisi ve Psöriasis

IgA Nephropathy and Psoriasis in a Child

Journal Name:

  • Türk Nefroloji, Diyaliz ve Transplantasyon Dergisi

Publication Year:

  • 2013
DOI: 
10.5262/tndt.2012.1003.25

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
IgA nephropathy is the most common primary glomerulonephritis worldwide. Painless macroscopic hematuria is frequent in children and often coincides with infections of the upper respiratory tract and/ or digestive system. The distinctive carbohydrate side chains of IgA1 molecules play an important role in the pathogenesis of IgA nephropathy. Defi nitive diagnosis of IgA nephropathy requires evaluation of a renal biopsy specimen. Psoriasis is also a common childhood chronic skin disease with changes in epidermal differentation and proliferation. There are also a few literature reports on the co-existence of IgA nephropathy and psoriasis mainly in adult patients. Herein, we report a child with psoriasis who was diagnosed as Ig A nephropathy after periods of painless hematuria.
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Abstract (Original Language): 
IgA nefropatisi (IgAN) primer glomerulonefrit nedenlerinin başında gelir. Ağrısız makroskobik hematüri çocuklarda sık görülür ve genellikle üst solunum yolu ve/veya sindirim sistemi enfeksiyonları ile birliktelik gösterir. IgA1 molekülünün farklı karbonhidrat yan zincirleri, IgAN’nin patogenezinde önemli rol oynamaktadır. IgAN’nin kesin tanısı renal biyopsi gerektirmektedir. Psöriasis epidermal farklılaşma ve proliferasyon ile giden çocukluk çağının sık görülen kronik deri hastalığıdır. Literatürde sadece erişkin hastalarda, IgAN ve psöriasis hastalığı birlikteliği bildirilmiştir. Biz bu yazıda hematüri semptomu ile izlenip IgAN tanısı alan ve psöriasis geliştiren bir pediatrik olgu sunduk.
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315
  • Turkish

REFERENCES

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