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Mide ve Kolorektal Kanserli Hastalarda Chitin'in Böbrek ve Karaciğer Fonksiyonlarına Etkisi

The effect of Chitin on kidney and liver function in patients with stomach and colorectal cancer

Journal Name:

  • Selçuk Tıp Dergisi

Publication Year:

  • 2011

Key Words:

Keywords (Original Language):

Author NameUniversity of Author
Abstract (2. Language): 
The effects of Chitin molecules, used prevention of abdominal adhesions, on organ functions were investigated. 40 patients, underwent surgery for gastric cancer and colorectal cancer and resectable initiatives were included in this study. After surgery, two Chitin Suprofilm ® in size of 15X10 cm were placed under the incision line. AST, Creatinin, BUN levels were measured in patients at preoperative, postoperative 1st and 5th days. There was no statistically significant difference in means of Creatinin, AST, and BUN levels between groups in three measurement. Having used Suprofilm® (Chitin) with adequate hydration, liver and kidney dysfunction was not developed. We think that Suprofilm® (Chitin) can be used safely as antiadhesive.
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Abstract (Original Language): 
Karın içi yapışıklıkların önlenmesinde kullanılan chitin molekülünün organ fonksiyonlarına olan etkisinin araştırılması. Bu çalışmaya mide kanseri ve kolorektal kanser nedeniyle ameliyat edilen ve rezektabl girişimler yapılan 40 hasta dahil edildi. Operasyon sonrası hastaların kesi hattı altına 15x10 cm. boyutta 2 adet Chitin Suprofilm® konuldu. Hastalarda preoperatif, postoperatif l.gün ve 5.günlerde AST, Creatinin, BUN değerlerine bakıldı. Her 3 ayrı AST, Creatinin ve BUN değerleri arasında gruplar içi ve gruplar arası değerlendirmede istatistiksel olarak anlamlı bir fark gözlenmedi (p>0.05). Hastalarda 2 tabaka Chitin kullanımından sonra yeterli hidrasyon sağlanmasıyla karaciğer ve böbrek fonksiyon bozukluğu gelişmemiştir. Chitinin antiadeziv olarak güvenle kullanılabileceği kanaatindeyiz.
FULL TEXT (PDF): 
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  • 3
134-136
  • Turkish

REFERENCES

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