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Orta kulak cerrahisinde farklı anestezi yöntemlerinin postoperatif bulantı, kusma ve derlenme üzerine etkileri

The effects of different anaesthetic methods on nausea-vomiting and recovery in the middle ear surgery.

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Abstract (2. Language): 
TThe aim of this study is to investigate the effects of sevoflurane and propofol anesthesia on postoperative nausea vomiting and recovery İn the middle ear surgery. The patients undergoing to middle ear surgery were randomly divided into two groups as Group S (n=19) and Group P ( n=19). AH the patients are premedicated with 0.1 mg/kg İM midazolam and the induction was done with sevoflurane in Group S and 2.5 mg/kg İV propofol in Group P. After the blockage with vecuronium 0.1 mg/kg, entübation was performed. Anesthesia maintenance was done with sevoflurane 1-3% in Group S and 8 mg/kg /h IV propofol infusion in Group P and 70% N20/02 inhalation in both. At the end of the operation, after quitting the anesthetics, the extubation times, spontaneous eye opening and recovery times were recorded. Postoperative nausea vomiting were evaluated in 2nd, 6th, 12th, 18th and 24th hours. There were no significant differences found betvveen the groups according to spontaneous eye opening and recovery times ( p>0.05). Nausea-vomiting rate was found to be high in 0-2, 2-6, 12-18 hours in Group S (p<0.05), but there was no difference in 6-12 hours ( p>0.05). Nausea-vomiting was not seen in any of the groups in 18-24 hours. İn conciusion no differences were found between ihese anesthesia methods according to postoperative recovery, although nausea-vomiting rates appearently lower in Group P. For this reason propofol anesthesia was decided to be an alternative for the middle ear surgery which has a high incidence of postoperative nausea and vomiting.
Abstract (Original Language): 
Bu çalışmada, orta kulak cerrahisinde sevofluran ve propofol uygulanan anestezi yöntemlerinin postoperatif bulantı kusma ve derlenme üzerindeki etkilerinin ortaya konması amaçlanmıştır. Bu amaçla orta kulak cerrahisi planlanan 38 olgu rastgele seçimle Grup S (n=19) ve Grup P (n- 19) olarak iki gruba ayrıldı. Her iki gruba da 0.1 mg/kg İM midazolam ile premedikasyon uygulandıktan sonra, anestezi indüksiyonu Grup S olgularda sevofluran inhalasyonu, Grup P olgularda ise 2.5 mg/kg İV propofol ile sağlandı. 0.1 mg/kg İV vekuronyum ile nöromusküler blok sağlandıktan sonra endotrakeal entübasyon yapıldı. Anestezi idamesi Grup S'de %1-3 sevofluran %70 N20/O2 inhalasyonu, Grup P'de 8 mg/kg/saat propofol ve %70 N20/02 inhalasyonu ile yürütüldü.Operasyonun bitiminde anesteziklerin kesilmesinden itibaren ekstübasyon süresi, spontan göz açma süresi, derlenme süresi kaydedildi. Bulantı, kusma ve öğürme postoperatif 0-2, 2-6, 6-12, 12-18 ve 18-24. Saatlerde değerlendirildi. Gruplar arasında ekstübasyon süresi, spontan göz açma süresi ve derlenme süreleri açısından anlamlı farklılık saptanmadı (p>0.05). Bulantı kusma ve öğürme 0-2, 2-6 ve 12-18. Saatlerde Grup S olgularda istatistiksel anlamda yüksek bulunurken ( p<0.05 ), 6-12. Saatlerde farklılık saptanmadı ( p>0.05 ). 18-24. Saatlerde her iki grupta da bulantı kusma ve öğürme görülmedi. Sonuç olarak bu farklı anestezi yöntemlerinin postoperatif derlenme üzerinde belirgin farklılıkları olmamasına rağmen. Grup P olgularda bulantı kusma oranının belirgin olarak az olması nedeniyle, postoperatif bulantu kusma riski yüksek olan ona kulak girişimlerinde propofolün iyi bir alternatif olabileceği kanısına varıldı.
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