You are here

Çocuklarda Üriner Sistem Enfeksiyonlarında Tedavi

Treatment of Urinary Tract Infection in Children

Journal Name:

Publication Year:

Keywords (Original Language):

Abstract (2. Language): 
Urinary tract infections are the most common bacterial infections in childhood. Although there are many antibiotics that are effective on their causative agents, it has still not been possible to prevent chronic cases. The main reasons are the various factors related to the host and the microor-ganism together with ineffective treatment methods and developing resistance to antibiotics. In conclusion, there was high resistance against the ampicil-lin, ampicillin-sulbactam, amoxicillin-clavulanic acid, co-trimoxazole and cephalosporins that are frequently used empirically in childhood urinary tract infections. It is there-fore necessary to review the treatment according to the antibiogram when these antibiotics are started initially. Treatment and prophylaxis has to be planned according to the antimicrobial resistance pattern found in the epidemio-logical data of each country and region.
Abstract (Original Language): 
İdrar yolu enfeksiyonları, çocukluk çağı enfeksiyon hasta-lıkları içinde en sık görülen bakteriyel enfeksiyonlardır. İdrar yolu enfeksiyonlarında sık görülen etkenleri etkileye-bilecek çok sayıda antibiyotik bulunmasına rağmen, bu enfeksiyonlarda kronikleşme ortadan kaldırılamamıştır. Bunun nedeni konağa ve mikroorganizmaya ait çeşitli faktörlerin yanı sıra, etkin olmayan tedavi yöntemleri veya antibiyotiklere karşı gelişen dirençtir. İdrar yolu enfeksiyonu olan çocuklarda ampirik olarak sık kullanılan ampisilin, ampisilin–sulbaktam, amoksisilin–klavunatik asit, TMP-SMX ve sefalosporinlere karşı diren-cin yüksek olduğu, bu nedenle de başlangıç tedavisi olarak bu antibiyotikler seçildiğinde antibiyotik duyarlılık testine göre tedavinin tekrar gözden geçirilmesi gerekmektedir. Her ülke ve her bölgenin kendi epidemiyolojik verilerinde-ki antimikrobiyal direnç özelliklerine göre tedavi ve profi-laksi planlarını düzenlemesi gereklidir.
105
111

REFERENCES

References: 

1. Cataldi L, Mussap M, Fanos V. Urinary tract infections in infants and children. Congress Report. 3 May 2006.
2. Sobel JD. Pathogenesis of urinary tract infec-tion. Role of host defenses. Infect Dis Clin North Am 1997 Sep;11(3):531-49.
3. Sirin A, Emre S, Alpay H, et al. Etiology of chronic renal failure in Turkish children. Pediatr Nephrol 1995; 9(5):547-52.
4. Öner A, Bülbül M, Demircin G, Erdoğan Ö. Etiology and outcome in 174 children with chronic renal failure. Ped Nephrol 2000:16,8(6):L95,P196.
5. M.Bülbül, K.Bek, Ö.Erdoğan, A. Delibaş, G.Demircin, A. Öner. VUR: Çocuklarda Kronik Böbrek Yetmezliğinin Önemli Bir Nedeni. Antal-ya :19. Ulusal Nefroloji Hipertansiyon Diyaliz ve Transplantasyon Kongresi, 2002, Antalya.
6. Newman T, MD, Bernzweig A, Takaya-ma J, Finch S. Urine Testing and Urinary Tract Infections in Febrile Infants Seen in Office Set-tings. Arch Pediatr Adolesc Med 2002;156:44-54.
7. Swerkerson S, Jodal U, Sixt R, Stokland E, Hansson S. Relationship among vesicourete-ral reflux, urinary tract infection and renal da-mage in children. J Urol 2007 Aug;178(2):647-51
8. Steven L, Chang MD, Linda D, et al. Pediatric urinary tract infections. Pediatr Clin N Am 2006;53(3):376-400.
9. Long SS, Klein JO. Bacterial infections of urinary tract. In: Remigton JS, Klein JO, eds. Infectious diseases of fetus and newborn in-fants, 6th edn. Philadelphia: WB Saunders, 2006:335-46.
10. Szlyk GR, Williams SB, Majd M, Belman AB, Rushton HG. Incidence of New Renal Pa-renchymal Inflammatory Changes Following Breakthrough Urinary Tract Infection in Pati-ents With Vesicoureteral Reflux Treated With Antibiotic Prophylaxis: Evaluation by 99mTechnetium Dimercapto-Succinic Acid Renal Scan. J Urol 2003 Oct;170(4Pt 2):1566-8
11. Loening-Bauche V. Urinary incontinan-ce and urinary tract infection and their resolu-tion with treatment of chronic constipation of childhood. Pediatrics 1997;2:228-32
12. Gür D. Bakterilerde antibiyotiklere karşı direnç, Enfeksiyon Hastalıkları ve Mikrobiyoloji-si. Ed; Topçu AW, Söyletir G ve Doganay M, 2002;1.cilt:182-192.
13. Erdem H, Avcı A ve Pahsa A. Toplum kaynaklı üropatojenik Escherichia coli suşların-da antibakteriyel direnç. Ankem Dergisi 2004;18(1):40-44.
14. Canbaz S, Peksen Y, Sunter AT, Leblebi-cioglu H ve Sunbul M . Antibiotic prescribing and urinary tract infection. Int J Antimicrobial Agents 2002;20:407-411.
15. Kocagöz S. Üriner sistem infeksiyonla-rında direnç sorunu, Enfeksiyon Hastalıkları. Ed; Uzun Ö ve Ünal S, Bilimsel Tıp Yayınevi, Ankara. 2001;1. Cilt:373-378
16. Zhanel GG, Hisanaga TL, Laing NM, DeCorby MR, Nichol KA, Weshnoweski B et al. final results from the North American Urinary Tract Infection Colaborative Alliance (NAUTI-CA). Antibiotic resistance in Escherichia coli outpatient urinary isolates. Int J Antimicrobial Agents 2006; 27:468-475.
17. Miller LG, Tang AW. Treatment of un-complicated urinary tract infections in an era of increasing antimicrobial resistance. Mayo Clinic Proceedings, 2004;79(8):1048-1054.
18. Çolak H. Üst üriner sistem infeksiyonla-rı, Enfeksiyon Hastalıkları. Ed; Uzun Ö ve Ünal S, Bilimsel Tıp Yayınevi, Ankara. 2001;1.cilt,343-355.
19. American Academy of Pediatrics, Committe on Quality Improvement, Subcom-mittee on Urinary Tract Infection. Practice Pa-rameter: The diagnosis, treatment, and evalu-tion of the initial urinary tract infection in febri-le infants and young children. Pediat-rics,1999;103:843-852 .
20. Gauthier M, Chevalier I, Sterescu A, et al. Treatment of urinary tract infections among febrile young children with daily intravenous antibiotic therapy at a day treatment center. Pediatrics 2004;114(4):469-76.
21. Baumer JH. Urinary tract infection in children diagnosis, treatment and long-term management : National Collaborating Centre for Women’s and Children’s Health Commissi-oned by the National Institute for Health and Clinical Excellence August 2007.
22. Gupta K. Emerging antibiotic resistance in urinary tract pathogens. Infect Dis Clin North Am 2003;17(2):243-59.
23. Jack S.Elder. Urologic disorders in in-fants and children. In: Behrman RE, Kliegman
Aydın ve ark.
Abant Med J 2014;3(1):105-111 111
RM, Jenson HB.(eds). Nelson Textbook of Pedi-atrics, 18 th ed.Saunders , Phildelphia 2007;1780-90.
24. Chon C, Lai F, Shortliffe LM. Pediatric urinary tract infections. Pediatr Clin N Am 2001;48:1441-1459.
25. Stephanie A.Lutter, MD, et al. Antibio-tic resistance patterns in children hospitalized for urinary tract infections. Arch Pediatr Ado-lesc Med 2005;159: 924-928.
26. Ashkenazi S, Even-Tov S, Samra Z, et al. Uropathogens of various childhood populati-ons and their antibiotic susceptibility. Pediatr Infect Dis J 1991;10(10):742-6.
27. Arrieta AC, Bradley JS. Empiric use of cefepime in the treatment of serious urinary tract infection in children. Pediatr Infect Dis J 2001;20(3):350-5.
28. Baskin MN, O’Rourke EJ, Fleisher GR. Outpatient treatment of febrile infants 28 to 89 days of age with intramuscular administration of ceftriaxone. J Pediatr 1992;120(1):22-7.
29. Hoberman A, Wald ER, Hickey RW, et al. Oral versus initial intravenous therapy for urinary tract infection in young febril children. Pediatrics 1999; 104:79-86.
30. Goldman JA, Kearns GL. Fluoroquinolo-ne Use in Paediatrics:Focus on Safety and Place in Therapy. WHO, 18th Expert Committee on the Selection and Use of Essential Medicines (2011).
31. Bacius V, Verrier-Jones K. Urinary tract infection. In: Cochat P (ed). European Society for Pediatric Nephrology Handbook. Medcom, Lyon 2002: 153-57.
32. Bing Dai, Yawei Liu, Jieshuang Jia, Changlin Mei. Long-term antibiotics for the prevention of recurrent urinary tract infection in children: a systematic review and meta-analysis. Arch Dis Child 2010;95:499-508
33. Conway PH, Cnaan A, Zaoutis T, et al. Recurrent urinary infection in children: risk factors and association with prophylactic anti-microbials. JAMA 2007;298(2):179-86.
34. Subcommittee On Urinary Tract Infec-tion, Steering Committee On Quality Improve-ment And Management. Urinary Tract Infec-tion: Clinical Practice Guideline forthe Diagno-sis and Management of the Initial UTI in Febrile Infants and Children 2 to 24 Months. Pediatrics 2011;128;595;

Thank you for copying data from http://www.arastirmax.com