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Anti TNF-α tedavisi alan romatoloji hastalarında dermatolojik yan etkiler

Dermatological side effects in rheumatological patients taking anti TNF-α treatment

Journal Name:

  • Abant Tıp Dergisi

Publication Year:

  • 2016
DOI: 
10.5505/abantmedj.2016.79058

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
dINeTrmROatDoUloCgTiIcOalN s: idIne tehfifse csttsu d(yD,S Ew)e s eaeimn eidn tpoa tinievnetsst iwgaitthe rMheEuTHmOatDicS :d Ais etaosteasl ntaukminbge Tr NoFf- α1 0b3lo pcakteire.n ts with chronic itnreflaatmmmenatt owrye rerh ienucmluadteicd idntisoe atshees stound y.T NAlFl -αcu tbalnoecokuesr lTeNisFo-nαs binlo cpkaetrie ntrtes awtmeeren tr. eTcoNrFd-eαd balos cbkeefros-rree laatnedd aDftSeEr dweemreo ggraropuhpice da nda sc liinnifceaclt icohuasr acatnedr istniocsn -oinf fpeacttiieonutss. wTihthe cDhSaEr aecxtearmisitnicesd .o fI nt haed pdaittiioenn,t sd wemitho girnafpehcticio uasn da ndcl inniocna-l iRnEfeSUctLioTuS:s D10S3E wpaetriee nctosm (p4a0r efedm. ale) between the age of l1e8is-7o4n sw oecrec uinrecdlu ddeudr iinngt oT tNhFe- αst ubdlyo.c kTeort atllrye a6t3m ceuntat nweoeures 7d eptesromriianseisd, i1n 5d0is (k%oi d4 8l.u5p4u) sp aetrieitnetms.a (t2o5z uosn, y1ch obmasyacl ocseisll, ccaurtcainneoomuas , les1io nsp.a) lm36o p(7la2n%ta) r of ppuasttieunlotssi sw, ith2 8D SEo thhaedr innofnec-itniofeucst isokuins lesskiionn. s.D 1S4E (3w8e%r)e ofs ipgantiifeicnatns twlyi thh iDghSEe rh aidn İpnafteiectniotsu s reDceSiEv inwg erceo ncsoigmniiftiacnatn tlmy ethhigohtreerx atteh an(M nToX)n. iTnhfeerceti owuass DnoSE r eilna tpioantsiehnipts b reetcweeiveinn gD ScEo nwciothm tithaen tty pMeT oXf. TDNISFC-αU SbSloIOckNe rA aNnDd CrhOeNuCmLUatSicIO dNis:e Aasse as .r esult, DSE ranging fbreo mse oenny cdhuorimngy cToNsiFs -tαo bmloaclikgenra nthcieersa pcayn. Mbeo sneiteonr indgu rifnogr iDmSpEo orft atnhte f poar teieanrltys drieacgeniovisnisg aTnNdF t-rαe abtlmoceknetr.
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Abstract (Original Language): 
nGeİRdİeŞn ivyele ATMNFA-Çα: bBliozk ebru tçeadlaışvmisai daal,a nr omhaasttiazmlaradl a,h atsetdalaığvıi ssaüpretasimncaey ı agmelaişçmlaidş ıko. lan dermatolojik yan etkileri (DYE) TYNÖFN-TαE bMlo kveer tGedEaRvEiÇsiL aElRa:n R10o3m hataisztma açla lhışamstaaylaığ ıd anheild eedniilydlei. sHoansrtaaslaı rodlaa rsaakp tkaanyadne dtiüldmi. TcNiltF -lαe zbyolonklearr ı,t etdeadvaivsii ösünrceecsiin dvee goelalirşaekn dgerrumplaatnodloırjıilkd ıl.e zyToendlaavr ie nsfüerkesicyinödz ev e DnoYnE -engefelikşstiiyreönz ehnasfetaklsaiyrıönz devme ognroafnik-e nvfee kksiniyiök z özDelYliEk lergi eilnişceenle nhdai.s tAaylarırcına dBeUmLGoUgrLaAfiRk: vBeu k inçaiklı şömzeal lidkale ryi akşalarşrııl a1ş8tı-r7ıl4d ı.a rasında değişen 1h0as3t ahdaas taT N(4F0-α k abdloınk)e dr etğeedralevni dsirüilrdeic. inTodep lagme li5ş0m i(ş% 6438 ,5c4ilt) lleuzpyuosn u etreistpemit aetdoizlduis ,( 251 o nibkoasmailk ozh, ü7c rpeslio riakzairsc, i1n odmis,k oid1 tpeadlmavoi pslüarnetcairn dpeu sDtYuElo zg,e l2iş8m idşi ğ5e0r hcailstt alneızny o3n6u ()%. 7A2n)t i‘ TsıNnFdαa emnefveckusitytöuz. , 1E4ş (%za3m8)a’n lüı ndme enthoont-reenxfaetkes iyö(Mz TcXilt) lekzuylolannlaarnı ahrassıtnadlaar dean fDekYsEi yöanz laDmYlEı ’ ollearriank, ndoanh-ae nsfıekk sbiuyöluzn doula. nBlaurndlaanr vaen lakumlllaı noıllaarna kT NdaFh-αa ybülokkseerk ioleld DuYğEu ‘g ölerrü ladrüa.s ıHnadsat aalnığlıanm tlaı nbısirı fTaArRk TbIuŞlMunAm vaed Sı.O NUÇ: TNF-α blokerler ile tedavi sürecinde, foanrikkloı mdeikrmoza todlaonji k myaanli gentiktielelerr gee likşaedbailri r. dSeoğnişueçn o layrealpk,a zTeNdFe- eαd bilmloekesir, eterkdeanv itsai naı lvaen thedasatvail aaçrıınsı,n dDaYnE ’ö lneerm alçidısiırn.
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