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İnterstisyal Dış Gebelik Olgusunun Sistemik Metotreksat ile Başarılı Bir Şekilde Tedavisi

Case report of a Successful Treatment of Interstitial Pregnancy with Systemic Methotrexate

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DOI: 
10.5505/abantmedj.2016.43660

Keywords (Original Language):

Abstract (2. Language): 
Ectopic pregnancy is the most common cause of morbidity and mortality in the first trimester of pregnancy. Interstitial pregnancy is one of the rarest form of ectopic pregnancies that constitutes of 2-4% of ectopic pregnancies. In this paper, we discussed the case of the interstitial pregnancy that successfully treated with systemic Methotrexate without requiring operation. Serial β-hCG were regressed without any need to further manipulations including operation. According to our clinical experience, in cases of interstitial pregnancies that hemodynamically stabilized and not having severe abdominal nor pelvic pain, systemic MTX treatment could be applied under serial USG and β-hCG follow-ups, that contribute low morbidity and mortality rates and lesser requirement to surgical approach
Abstract (Original Language): 
Ektopik gebelik ilk trimesterde morbidite ve mortalitenin en sık nedenidir. İnterstisyal gebelik ektopik gebeliğin en nadir formlarından olup tüm ektopik gebeliklerin %2-4’ünü oluşturmaktadır. Bu yazımızda girişime gerek kalmadan sistemik Metotreksat ile başarılı şekilde tedavi edilmiş interstisyal gebelik olgusunu tartıştık. Seri β-hCG ölçümlerinde yeterli regresyon izlendi ve operasyona ihtiyaç kalmadı. Klinik deneyimimize göre hemodinamik olarak stabil, batında ve pelviste ağrısı olmayan interstisyal gebeliği olan hastalarda sistemik MTX tedavisi seri β-hCG ölçümleri ile izlem yapılarak uygulanması cerrahiye gereksinimi azaltmakta ve de böylece morbidite ve mortaliteye de olumlu yönde katkıda bulunmaktadır.
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REFERENCES

References: 

1. Anon, Ectopic pregnancies: United States, 1990-
Sel G ve ark.
Abant Med J 2017;6(3):120-122 122
1992.MMWR Morb Mortal Wkly Rep 1995;44:46 48.
2. Lau S, Tulandi T. Conservative medical and surgical
management of interstitial ectopic pregnancy. Fertil Steril
1999;72:207-15.
3. Damario, M. A.; Rock, J. A. (2003). "Ectopic Pregnancy". In
Rock, J. A.; Jones, H. W. III. Te Linde’s Operative
Gynecology (9th ed.). Philadelphia: Lippincott Williams &
Wilkins. pp. 507–536.
4. Kerr LM, Anderson DF. Angular pregnancy: A clinical
entity. Br Med J 1934; 1: 1113-4
5. Bond AL, Grifo JA, Chervenak FA. Term interstitial
pregnancy with uterine torsion: sonographic, pathologic,
and clinical findings. Obstet Gynecol 1989; 73: 857-9
6. Stewart EA, Yeh J. The fallopian tubes and ectopic
pregnancy. In: Ryan KJ, Berkowitz RS, Barbieri RL, editors.
Kistner’s gynecology. 6th ed. St. Louis: Mosby-Year Book;
1995. p. 166-86.
7. Maliha WE, Gonella P, Degnan EJ. Ruptured interstitial
pregnancy presenting as an intrauterine pregnancy by
ultrasound. Ann Emerg Med 1991; 20: 910-2
8. Karsdorp VHM, Van der Veen F, Boer-Meisel ME,
Kenemans P. Successful treatment with methotrexate of
five interstiatial pregnancies. Hum Reprod 1992; 7:1164-9
9. Dilbaz S, Katas B, Demir B, Dilbaz B. Treating cornual
pregnancy with a single methotrexate injection: a report
of 3 cases. J Reprod Med 2005; 50: 141-4
10. Deniz Balsak, Murat İnal, Yusuf Yıldırım, R. Soner Öner,
Şivekar Tınar. Rüptüre Olmamış Kornual Gebeliğin
İntravenöz Methotrexate İle Başarılı Tedavisi: Olgu
Sunumu. İnönü Üniversitesi Tıp Fakültesi Dergisi 14(1) 65-
67 (2007)

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