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SYNTHESIS, CHARACTERIZATION AND PHARMACOLOGICAL EVALUATION OF NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES

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Abstract (2. Language): 
Benzimidazole derivatives have been described for their chemotherapeutic importance, also, the presence of basic Mannich side chains in a drug may overcome the water insolubility problem through the formation of hydrochlorides. The aim of this research work is to synthesize some benzimidazole derived compound. Some of these compounds showed potential antimicrobial activities.
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Ampicilline +++ +++ - -
2a ++ ++ - -
3a - - - -
3c ++ - - -
4a - - - -
4c - +
Deshbandhu Joshi, ARPB, 2011; Vol 1(1) ISSN 2250 - 0774
(Research paper)
www.arpb.info Page 50
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