You are here

Asbestos ve İzole Plevral Renal Hücreli Kanser Metastazı Arasındaki Olası İlişki

The Probable Relation Between Asbestos and Isolated Pleural Metastasis in Renal Cell Cancer

Journal Name:

Publication Year:

DOI: 
10.17954/amj.2016.46
Abstract (2. Language): 
The most common site for metastasis from renal cell carcinoma (RCC) is the lung parenchyma (50% of patients), followed by the skeleton (20% to 50% of patients). It is well known that RCC has a tendency to create atypical metastases (1, 2). Pleural lesions are infrequent and metastasis is usually associated with parenchymal lung lesions. Pleural metastasis without involvement of the lung parenchyma due to primary renal tumors is infrequent in the literature. If this happens, the main characteristics of metastasis in RCC are multiple lesions that are mostly in a nodular pattern and well demarcated (3). Whether or not the patients priorly diagnosed with RCC may represent with atypical metastasis in every stage of the disease. Asbestos is common in less developed countries and it can lead to increased risk and mortality of renal cell carcinoma (4, 5). Unfortunately along with the increased frequency of asbestos lead to causes late recognition of metastatic disease.
49
50

REFERENCES

References: 

1. H an KR, Pantuck AJ, Bui MH , Shvarts O, Freitas DG,
Zisman A, Leibovich BC, Dorey FJ, Gitlitz BJ, Figlin RA ,
Belldegrun AS : Number of metastatic sites rather than
location dictates overall survival of patients with nodenegative
metastatic renal cell carcinoma. Urology 2003;
61: 314- 9.
2. Z ekri J, Ahmed N, Coleman RE , Hancock BW. The
skeletal metastatic complications of renal cell carcinoma.
Int J Oncol 2001; 19:379-82.
3. Kutty Kesavan and Basil Varkey. Incidence and
distribution of intrathoracic metastases from renal cell
carcinoma. Arch Intern Med 1984;144:273-76.
4. I . J. Selikoff, E. C. Hammond, and H. Seidman. Mortality
experience of insulation workers in the United States and
Canada, 1943-1976. Ann N Y Acad of Sci 1979; 330:91-
116.
5. P . E. Enterline, J. Hartley, and V. Henderson. Asbestos and
cancer: A cohort followed up to death. Br J Ind Med 1987;
44:396-401.
6. Eckardt Jens, Lars Ladegaard and Peter Bjørn Licht.
Isolated pleural metastases from renal cell carcinoma.
Interact Cardiovasc Thorac Surg 2011; 12:301-02.
7. Taylor DR, Page W, Hughes D and Varghese G. Metastatic
renal cell carcinoma mimicking pleural mesothelioma.
Thorax 1987; 42: 901-02.
8. Attanoos RL , Goddard H, Thomas ND, Jasani B and
Gibbs AR . A comparative immunohistochemical study
of malignant mesothelioma and renal cell carcinoma: the
diagnostic utility of Leu-M1, Ber EP 4, Tamm-Horsfall
protein and thrombomodulin. Histopathology 1995; 27:
361-66.

Thank you for copying data from http://www.arastirmax.com