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ESTETİK restoratif materyallere enflamatuvar yanıtları [Kompozit, kompomer VE ormocer] SIÇANLARDA

INFLAMMATORY RESPONSES TO ESTHETIC RESTORATIVE MATERIALS [COMPOSITE, COMPOMER AND ORMOCER] IN RATS

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Abstract (2. Language): 
The aim of this study was to determine the acute non-speeific toxicity of esthetic restorative materials in rats. Blood samples for WBC counts were obtained just before and after one week of inoculation of the materials. When we compared die VVBC counts, there was a significant difference in WBC (p<0.05) with respect to all selected materials.The esthetic restorative materials were found to be biocompatible in the limits of this study, Nevertheless, the compomers were identified as more biocompatible than Iresin composite!. The results have shown that the WBC values that occurred as the natural result of Lhe infection arc the hemo-lolo^ical values that can represent the biocompatibility. The Duncan test made for WBC counts has showed that when compared with PVC, a toxic substance, the other three materials (composite, compomer, ormocer) can be assumed to be biocompatible.
Abstract (Original Language): 
Çalışmamızın amacı sıçanlarda estetik restoratif materyali erin akut nonspesifik toksisitclcrmin belirlenmesidir. Materyaller yerleştirilmeden önce vc ycrlcştini-dikten bir hafta sonra kan örnekleri alınmış vc bu örneklerde WBC değerlerine bakılmıştır. Bu değerler karşılaştırıldığında bütün materyeller arasında istatistiksel olarak anlamlı farklılık bulunmuştur (px0.05). Estetik restoratif materyaller çalışmamıza göre biyoııyumlu bulunmuşlardır. Bununla birlikte kompomcrler rezin konıpozitlcrc göre daha uyumlu bulunmuştur. Sonuçlar göstermiştir ki WRC değerleri enfeksiyon oluşumunu belirleyen hematolojik bulgu olarak biyouyum-lulıtğu yansıtabilir. WBC ortalamalarına uygulanan Duncan testine göre, toksik materyal olarak kabul edilen PVC ile karşılaştırıldığında diğer üç materyal (kompozit, kompomer,«rmocer) biyouyumlu kabul edilebilir.
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REFERENCES

References: 

1. Ruse ND. What is a "Compomer"7 J Can Dent Assoc 1999; 65(9): 500-504.
2. Hickcl R, Dasch W, Janda R, Tyas M, Anusavice
K. New direct restorative materials. Int [>en J 1998; 48(1): 3-16.
3. Lcfebvre CAS Schuster GS, Rueggeberg FA, Tamareselvy K, Knoemschild KL. Responses of oral epithelial cells to dental resin components. J Biomatcr Sci Folym Ed. 1996; 7(11}: 965-976,
4. Kawai K, Tsuchitani Y. Effects of resin composite components on glucosyltransferase of cariogenic bacterium. J Biomed Mater Res. 2000; 51(1):123-127.
YILDIZ,BAYINDIR, ZORBA, GÜMÜŞTEKİN
5. Domagala Z, Sliwa J, Hajek E. The preliminary evaluation of HAP+TCP composite material biodegradation after implantation in muscular tissue of rats. Polim Med 2001; 31(3-4); 52-60.
6. Santerrc JP, Shajii L, Leung BW. Critical Reviews in Oral Biology and Medicine. An official publication of American Association of oral biologists. 2001;12: 136-151¬7. Shajii L, Santerre JP. Effect of filler content on
the profile of released biodegradation products in micro-filled bis-GMATEGDMA dental composite resins. Biwnaterials I999;20{2Q): 1897-1908.
8. Munksgaard EC, Frcund M. Enzymatic hydrolysis of (di)methacrylates and their polymers. Scand J Dent Res. 1990; 98(3):261-267.
9. Hansasuta C. Neiders ME, Aguirre A, Cohen RE. Cellular inflammatory responses to direct restorative composite resins. J ProsthetDent 1993; 69(6):611-616.
10. Vevge P, Bergstrand H, Hakansson L, Neutrophils and eosinophils. In: Textbook of Rheumatology (Kellcy WN, Harris ED, Ruddy S, Sledge CB, eds.) Philadelphia: W.B. Saunders Company, 1997; ppl46.
11 _ Holland SM, Galin JI. Disorders of granulocytes and monocytes. In: Harrisons! principles of internal medicine {Fauchi A. S.. Braunvvald E( Isselbacher KJ, Wilson JD, Martin JB, Kasper DL, Hauser SL, Longo DL, eds.) Newyork.Mc Graw-Hill, 1998, pp 351.
12. Quinlan CA, Zisterer DM, Tipton KE, OfSullivan MI. In vitro cytotoxicity of composite reftin and compomer. Int Endod J 2000; 35(1): 47-55.
13. Hanks CT, Strawn SE, Wataha JC, Craig RG. Cytotoxic effects of resin components on cultured mammalian fibroblasts. J Dent Res 1991; 70(11): 1450-1455,
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Atatürk Üniv.Diş Hek.Fak.Derg. Cilt:14,Sayı2. Sayfa: 12-16,2004
YILDIZ, BAYINDIR, ZORBA, GÜMÜŞTEKİN
14. ReichJ FX, Dürner j, Manhart J, Spahl W, Gempel K, Kehe K, Licbl B, Walther UI, Hume WR, Hickel R. Biological clearance of HEMA in guinea pigs. Biomaterials 2002; 23(20): 2135-2141.
15. Bauer J G, Al-Rubayi A. Tissue response lo direct filling materials. J Proslhet Dent 1987; 58(5): 584-589,

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