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KAN TESTLERİ İLE DMFT SKORLARI, MİKROBİYOLOJİK SAYIM VE TÜKÜRÜĞÜN TAMPONLAMA KAPASİTESİ ARASINDAKİ KORELASYON

THE CORRELATION OF BLOOD TESTS WITH DMFT SCORES MICROBIOLOGIC COUNTS AND BUFFER CAPACITY OF SALIVA

Journal Name:

  • Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi

Publication Year:

  • 2012

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Over the last decade, there is an increasing interest in possible associations between oral and systemic diseases since the bacteria and/or their products are known to invade the systemic circulation. Besides the effects of carious tissue on other teeth, severe caries may have some consequences on the general health such as growth and weight gain retardation, upregulation of some systemic parameters of inflammation. In this study, the possible correlation of DMFT (decayed, missing, filled teeth) scores, with microbiologic counts, the buffer capacity of saliva and certain blood parameters such as blood cells counts and inflammatory cytokins has been analyzed in 152 patients with healthy periodontium. The results showed that in the presence of high s. mutans and lactobacilli and low buffer capacity, there was a statistically significant correlation between DMFT scores and Il-8, IgA, IgD, CD4, CD19 and eosinophiles. The results have indicated that also dental caries should be included in the perspective of oral health and systemic health, and they suggest that the dental and medical professions should develop even closer ties in the future
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Abstract (Original Language): 
Son zamanlarda sirkülasyona katılan oral bakteriler ve bakteri ürünleri ile sistemik hastalıklar arasında ilişki kurulmaya çalışılmaktadır. Çürük lezyonu dişte oluşturduğu harabiyet dışında, ilerlediği durumlarda da genel sağlıkla ilgili büyüme, kilo alımında problem, bazı sistemik inflamatuar parametrelerde artışa neden olmaktadır. Bu çalışmada DMFT (çürük, eksik, dolgulu diş) skorları, mikrobiyolojik sayım, tükürüğün tamponlama kapasitesi, kan hücreleri, inflamatuar hücreler gibi belirli kan hücrelerine ait parametreler, sağlıklı periodonsiyuma sahip 152 hastada analiz edilmiştir. Yüksek oranlarda S. Mutans ve Lactobacilli, düşük tamponlama kapasitesi varlığında DMFT skorları ile IL8, Ig A, Ig D, CD4, CD 19 ve eozinofil değerleri arasında istatistiksel olarak belirgin bir korelasyon elde edilmiştir. Sonuçlar oral sağlığın sistemik sağlık çerçevesinde değerlendirilmesi gerektiğini, diş hekimleri ile tıp doktorları arasında hasta ile ilgili iletişimin olması gerektiğini göstermektedir.
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PDF icon arastirmax-kan-testleri-ile-dmft-skorlari-mikrobiyolojik-sayim-tukurugun-tamponlama-kapasitesi-arasindaki-korelasyon.pdf
  • 1
14-19
  • Turkish

REFERENCES

References: 

1. Newman HN. Focal sepsis- modern concept. J Ir
Dent Assoc 1968;14:53-63.
2. Newman HN. Focal infection. J Dent Res
1996;75:1912-9.
3. Li X, Kolltveit K, Tronstad L, Olsen I. Systemic
diseases caused by oral infection. Clin Microbiol
Rev 2000;13:547-558.
4. Gibbs RS. The relationship between infections and
adverse pregnancy outcomes:an overview. Ann
Periodontol 2001;6:153-63.
5. de Soet JJ, Schriks MCM, Kratz E, Poland DCW,
van Dijk W, van Amerongen WE. Dental caries
related to plasma IgG and alpha1 – acid
glycoprotein. Caries Res 2003; 37:79-84.
6. Yoshihara A, Hanada, Miyazaki H. Association
between serum albumin and root caries in
community-dwelling older adults. J Dent Res
2003;82:218-222.
7. Hahn CL, Best AM, Tew JG. Comparison of Type 1
and Type 2 Cytokine production by mononuclear
cells cultured with Streptococcus mutans and
selected other caries bacteria. J Endodon
2004;30:333-8.
8. Izumi T, Kobayashi I, Okamura K, Matsuo K,
Kiyoshima T, Ishibashi Y, Inoue H, Sakai H. An
immunohistochemical study of HLA-DR and alpha
1-antichymotrypsin-positive cells in the pulp of
human non-carious and carious teeth. Arch Oral
Biol 1996;41:627-30.
9. Hahn CL, Best AM, Tew JG. Cytokine Induction by
Streptococcus mutans and pulpal pathogenesis.
Infect Immun 2000;68:6785-89.
10. Baum LJ. Dental pulp conditions in relation to
carious lesions. Int Dent J 1970;20:309.
11. Ivanyi L, Lehner T. The relationship between caries
index and stimulation of lymphocytes by
Streptococcus mutans in mothers and their
neonates. Arch Oral Biol 1978;23:851-6.
12. Izumi T, Kobayashi I, Okamura K, Sakai H.
Immunohistochemical study on the
immunocompetent cells of the pulp in human noncarious
and carious teeth. Arch Oral Biol
1995;40:609-14.
13. Moore MA, Gregory RL, Switalski LM, Hakki ZW,
Gfell LE, Kowolik MJ. Differential activation of
human neutrophils by Streptococcus mutans
isolates from root surface lesions and caries-free
and caries-active subjects. Oral Microbiol Immunol
1998;13:41-6.
14. Jontell M, Okiji T, Dahlgren U, Bergenholtz G.
Immun defense mechanisms of the dental pulp.
Crit Rev Oral Biol Med 1998;9:179-200.
15. Pezelji-Ribaric S, Anic I, Brekalo I, Miletic I, Hasan
M, Simunovic-Soskic M. Detection of tumor
necrosis factor alpha in normal and inflamed
human dental pulps. Arch Med Res 2002;33:482-4.
16. Nakanishi T, Matsuo T, Ebusi S. Quantitative
analysis of immunoglobulins and inflammatory
factors in human pulpal blood from exposed pulps.
J Endod 1995;21:131-6.17. Challacombe SJ, Bergmeier LA, Rees AS. Natural
antibodies in man to aprotein antigen from the
bacterium Streptococcus mutans related to dental
caries experience. Arc Oral Biol 1984;29:179-84.
18. Parkash H, Sharma A, Banerjee U, Sidhu SS,
Sundaram KR. Differential cell-mediated immune
response to S. mutans in children with low and
high dental caries. Indian Pediatr 1993;30:991-5.
19. Aaltonen AS, Tenovuo J, Lehtonen OP, Saksala R.
Maternal caries incidence and salivary closecontacts
with children affect antibody levels to
Streptococcus mutans in children. Oral Microbiol
Immunol 1990;5:12-8.
20. Geerts SO, Nys M, De MP, Charpentier J, Albert A,
Legrand V, Rompen EH. Systemic release of
endotoxins induced by gentle mastication:
association with periodontitis severity. J
Periodontol 2002;73:73-8.
21. Zhang P, Jespersgaard C, Lamberty-Mallory L, Katz
J, Huang Y, Hajishengallis G, Michalek SM.
Enhanced immunogenicity of a genetic chimeric
protein consisting of two virulence antigens of
Streptococcus mutans and protection against
infection. Infect Immun 2002;70:6779-87.

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