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Renal Iskemi-Reperfüzyonu Sırasında Sıçan Böbreğinde Olusan Oksidatif Stres Hasarına Silimarin Etkisi

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Abstract (2. Language): 
Renal ischemia reperfusion injury is the most common causes of acute renal failure. Silybum marianum L. Gaertn. (milk thistle) is a plant which belongs to Asteraceae family. Silymarin is a plant derived flavonoid which is extracted from the seeds of the S. marianum L. In this study, we investigated the protective effect of silymarin during the experimental renal ischemia reperfusion injury in rats histologically and biochemically.
Abstract (Original Language): 
Renaliskemi reperfüzyon hasarı akut böbrek yetmezliğinin temel sebebidir. Silybum marianum L. Gaertn. (devedikeni), Asteraceae familyasına ait bir bitkidir. Silimarin, S. marianum L. tohumlarından elde edilen bitkisel kaynaklı bir flavonoiddir. Bu çalışmada silimarinin, deneysel renal iskemi reperfüzyon sırasında olusan hasar Üzerine koruyucu etkileri histolojik ve biyokimyasal olarak arastırıldı.
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