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KORONER ANJİOPLASTİ UYGULANAN KADIN VE ERKEK HASTA GRUPLARINDA SAPTANAN FARKLI ÖZELLİKLER

Journal Name:

  • Cerrahpaşa Tıp Dergisi

Publication Year:

  • 2000

Key Words:

Keywords (Original Language):

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Abstract (2. Language): 
Female and male patients with coronary artery disease (CAD) have significant differences to each other. To evaluate these differences which lead us to choose the optimal strategy for diagnosis and treatment, we compared some features of female and male patients (pt)s who underwent percutaneous transluminal coronary angioplasty (PTCA) procedure in our interventional cardiology department. Results.- 3400 pts underwent (PTCA) procedure and stent implantation, between years 1991 and 1998. 600 (18%) of the pts were female and 2.800 (82%) were male. Mean age, procedural success rate, risk factors, the location of the lesion in the coronary tree, types of the lesions, restenosis rate and mean values of stent diameters among different pt groups were compared in female and male pts. Mean age values were higher in female pts (female: 59.5±10, male: 54.7±9, p<0.0001). Procedural success rate were nearly same (female: 93.5%, male: 94.5%, p:ns). When we compared the risk factors in a group of 158 pts; hypertension (female: 53.8%, male: 28.7%, p<0.02) and hypercholesterolemia (female: 46.1%, male: 19.6%, p<0.01) were higher in female pts. Diabetes (female: 19%, male: 12%, p: ns), family history of CAD (female: 46%, male: 29%, p: ns) and smoking (female: 23%, male: 39.6%, p: ns) were no more different in two groups. Restenosis rate were 23% in female and 30% in male pts among 308 sequential pts (p: ns). The location of the lesions in the coronary tree (LAD, CXA, RCA) and the types of the lesions (A, B, B2, C) among 1240 sequential pts showed no significant differences between two groups. When we compared the stent diameters of 647 pts, it was lower in female pts than in males (females: 3.18±0.4 mm, males: 3.32± 0.3 mm) (p<0.0001). Conclusion.- Procedural success rate, diabetes, family history of CAD, smoking, restenosis rate, the location of the lesions in the coronary tree, the types of the lesions were not significantly different in male and female pts. Mean age values, hypertension and hypercholesterolemia were significantly higher and stent diameter mean value was lower in female pts.
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Abstract (Original Language): 
Koroner arter hastalığı bulunan kadın hastalar, erkek hastalara göre farklılıklar göstermektedir. Bize tanı ve tedavide yol gösterici olan bu farklı özellikleri irdelemek amacıyla; kliniğimizde perkütan translüminal koroner anjioplasti (PTKA) uygulanan kadın ve erkek hastaların çeşitli özelliklerini karşılaştırdık. Kliniğimizde 1991-1998 yılları arasında 3400 hastaya perkütan trans-lüminal koroner anjioplasti (PTKA) ve stent uygulamas ı yapıldı. 600’ü (%18) Kadın, 2.800’ü (%82) erkek olan bu hastaların yaş ortalamalar ı, işlem başarı oranı, risk faktörleri, lezyonun yerleştiği damarların dağılımı, lezyon tiplerinin dağılımı, restenoz oranı ve stent çapı ortalama değerleri değişik hasta gruplarında karşılaştırıldı. Çalışmamızda kadın hastaların yaş ortalamas ı yüksek bulundu (kadın: 59.5 ± 10, erkek: 54.7 ± 9, p<0.0001). İşlem başar ı oranı eşitti (kadın: %93.5, erkek: %94.5, p:ns). Sıralı 158 hastada yapılan risk faktörleri karşılaştırmasında, hipertansiyon (kadın: %53.8, erkek: %28.7, p<0.02) ve hiperkoles-terolemi (kadın: %46.1, erkek:% 19.6, p<0.01) kadınlarda yüksek, diabet (kadın: %19, erkek:%12, p:ns) ve aile anamnezi (kadın: %46, erkek:%29, p: ns) her iki grupta farksız, sigara anamnezi (kadın: %23, erkek:%39.6, p:ns) ise erkeklerde yüksek bulundu. Restenoz oranı sıralı 308 hastanın değerlendirmesinde kadın hastalarda (%23) erkeklere (% 30) göre hafif düşük olmakla beraber fark anlamlı bulunmadı . Tüm hastalarda değerlendirilen lezyon yerleşimi (LAD, CXA, RCA) ve 1240 hastada değerlendirilen lezyon tipleri (A, B, B2, C) her iki grupta eşit oranlarda bulundu. Damar çaplarını kıyaslamak amacıyla 647 hastada uygulanan stent çaplarının ortalama değeri kad ın ve erkek hastalarda karşılaştırılınca kadınlarda (3.18 ± 0.4 mm) bu değerin erkeklerden (3.32±0.3 mm) düşük olduğu görüldü (p< 0.0001). Sonuç olarak: geriye dönük olarak yapı- lan bu incelemede kadın ve erkek hastalarda; işlem başarı oranı, diabet, sigara ve ailede koroner arter hastalığı anamnezi, restenoz oranı, lezyonun damarlara yerleşimi, lezyon tipleri anlamlı farklılık göstermemiştir. Kadın hastalarda; yaş ortalamas ı, hipertansiyon ve hiperkolesterolemi sıklığı anlamlı derecede yüksek, stent çapı ortalama değeri ise anlamlı derecede dü- şük bulunmuştur.
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  • 4
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  • Turkish

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