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PLEVRANIN SOLİTER FİBRÖZ TÜMÖRÜ İLE İZLEDİĞİMİZ 3 OLGU

Journal Name:

  • Cerrahpaşa Tıp Dergisi

Publication Year:

  • 2002

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Solitary fibrous tumors of the pleura are very rare neoplasms. The majority of these tumors is benign, but about 10-20% fulfills the criteria of malignancy. Clinical presentation varies according to the size and intrathorasic localization. In early stages, though the tumors may gradually grow to enourmous size and then cause symptoms such as cough, chest pain and dyspnea, also paraneoplastic syndromes such as hypoglisemia or digital clubbing. Histologically, they are characterized by fibroblast-like cells and connective tissue in varying proportions. The majority of solitary fibrous tumors are immunoreactive for CD34. Surgical resection is usually curative. Observation.- We reported three cases with solitary fibrous tumor of pleura. Their clinical, radiologic, histologic and immunhistochemical features were emphasized with a review of related current knowledge.
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Abstract (Original Language): 
Soliter fibröz tümör plevranın nadir bir tümörü olup genellikle selimdir. Ancak olgular ın %10-20’si malinite kriterlerini göstermektedir. Klinik bulgular genellikle tümörün büyüklüğüne ve yerleşim yerine göre değişmektedir. Erken dönemde olguların çoğu asemptomatik olmakla birlikte tümör boyutlar ının artmasıyla öksürük, göğüs ağrısı, nefes darlığı gibi torasik semptomlar, hipoglisemi veya çomak parmak gibi ekstrapulmoner semptomlar görülebilmektedir. Histolojik olarak tümör, fibroblast benzeri hücreler ile bağ dokusu elemanlarından oluşmaktadır. Tümör hücreleri genellikle CD34 ile pozitiftir. Tümörün cerrahi olarak çıkarılması tedavide yeterlidir. Bu yazıda, plevrada soliter fibröz tümör tanısı alan üç olgunun klinik, radyolojik, histolojik ve immunhistokimyasal özellikleri, son literatür bilgileri ışığı alt ında irdelenmektedir.
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  • 2
127-131
  • Turkish

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