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Tis/ T1/T2 EVRELERİNDEKİ MİDE KARSİNOMU OLGULARINDA KÜRATİF REZEKSİYON SONUÇLARI

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Abstract (2. Language): 
Despite recent improvements in the diagnostic accuracy and techniques for early gastric carcinoma, some patients die of a recurrence, even after resection of an early gastric cancer, (EGC). It has been suggested that patients with T2. No carcinoma of the stomach has a comparable survival rate to patients with T1 carcinoma of the stomach. Study design.- Clinicopathologic features and survival rates of 50 patients with Tis/T1/T2 adenocarcinoma of stomach treated between 1989 to 1993 were reviewed. Prognostic significance of the clinicopathologic features in gastric carcinoma with invasion confined to the stomach wall was studied using both a univariate and a multivariate analysis. Results.- Excluding deaths from causes other than recurrence, five-year survival rate for patients with Tis/T1 carcinoma of stomach was 100 percent. Five-year survival rate for patients with T2 carcinoma of the stomach was 68.8 percent. Conclusions.- In patients with gastric carcinoma with invasion confined to the stomach wall, most important prognostic factor was lymph node invasion.
Abstract (Original Language): 
1989-1993 yılları arasında, İstanbul Üniversitesi, Cerrahpaşa Tıp Fakültesi, Genel Cerrahi Anabilim Dalında, primer mide adenokarsinomu sebebiyle rezeksiyon uygulanan 278 hastadan 50’sinde serozal invazyon bulunmadığını yani Tis/T1 ve T2 evrelerinde bulundukları tespit edildi. Bu retrospektif araştırmada, hatsalar ın en erken 5,5 sene, en geç 8 senelik uzun evreli takip sonuçları öğrenildi; ancak 2 hastaya ulaşılamadı. En az, geniş lokal eksizyon (3 olguda), çoğunlukla Distal Gastrektomi (28 olguda) uygulanan hastalarda Tis/T1 olgularında 5 yıllık sürvi %100 iken , T2 tümörlü olgularda 5 yıllık sürvi %68,8’dir. Nüks sebebiyle 5 yıl yaşayamayan T2 evresindeki tümörlü olgularda, lenf nodülü metastazı %91,6 iken, %8,3’de lenf nod ülü metastazı bulunmadığı tespit edilmiştir. Sonuç olarak serozal invazyon yapmamış, primer mide karsinomu olgularında, küratif rezeksiyon sonrası sürviyi etkileyen başlıca faktörün metastatik lenf nodüllerinin mevcudiyeti olduğu anlaşılmıştır.
209-213

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