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Preoperatif Yüksek C-Reaktif Protein Seviyesi Kardiyak Cerrahi Sonrası İnfeksiyonu Yansıtır mı?

Does preoperative high level C-reactive protein reflect infection after cardiac surgery?

Journal Name:

  • Cerrahpaşa Tıp Dergisi

Publication Year:

  • 2008

Key Words:

Keywords (Original Language):

Author Name
Abstract (2. Language): 
Objectives: C-reactive protein (CRP) is an acute phase protein which increases the fastest after inflammation or tissue injury and which decreases the fastest during recovery period. The measurement of the preoperative CRP level can be used for determining the risk for development of infection following cardiac surgery. Methods: Thirty consecutive patients who had open cardiac surgery between January 2001 and May 2001 at Dr. Siyami Ersek Hospital were evaluated. The CRP levels of the patients whose temperature being followed up were measured preoperatively and in postoperative days 1, 4 and 6. The normal level for CRP was accepted to be 5 mg/l or less. Results: We concluded that the preoperative CRP levels in the group who had infection postoperatively were higher than the group without infection (23.21±6.98 vs 5.21±1.41). Two patients had superficial wound infection, 3 had urinary tract infection and 1 had pneumonia. No death was detected. Conclusion: It should be taken into account that the measurement of the preoperative CRP levels can contribute to prevent postoperative mortality and morbidity that might progress after surgery beforehand.
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Abstract (Original Language): 
Amaç: C- reaktif protein (CRP), inflamasyon veya doku hasarı sonrasında en hızlı yükselen ve iyileşme süresinde en hızlı düşen akut faz proteinidir, preoperatif CRP düzeyinin ölçümü, kalp cerrahisi sonrası infeksiyon gelişme riski olan hastaları belirlemek için kullanılabilir. Yöntem: Dr. Siyami Ersek Hastanesinde Ocak 2001-Mayıs 2001 arasında açık kalp cerrahisi yapılan ardışık 30 hasta prospektif olarak de- ğerlendirmeye alındı. Sürekli ateş takibi yapılan hastaların preoperatif, postoperatif 1.gün, 4. gün, 6. gün CRP değerlerine bakıldı. CRP immünoturbidimetrikal yöntemlerle bakıldı ve normal değeri 5mg/l ve altı olarak kabul edildi. Bulgular: Postoperatif dönemde infeksiyon gelişen grubun preoperatif CRP değerlerinin (23.21±6.98), infeksiyon gelişmeyen gruptan (5.21±1.41) yüksek olduğunu gördük (p<0.001). 2 hastada yüzeyel yara yeri infeksiyonu, 3 hastada idrar yolu enfksiyonu, 1 hastada pnömoni görüldü. Hastaların hiçbirinde ölüm görülmedi. Sonuç: Preoperatif CRP değerlerinin ölçümü, operasyon sonrası gelişebilecek mortalite ve morbiditenin önceden önlem alınmasına katkıda bulunabileceğini gözönünde bulundurmak gerekir.
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  • 4
144-149
  • Turkish

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