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Sirotik Olmayan Portal Hipertansiyon ve Gebelik Sonuçları

Non-cirrhotic portal hypertension and pregnancy outcome

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Abstract (2. Language): 
Objectives: The aim of the present study was to evaluate complications during pregnancy and pregnancy outcome in women with non-cirrhotic portal fibrosis and portal hypertension. Methods: Eight pregnancies with non-cirrhotic portal fibrosis and portal hypertension managed in our clinic between January 1998 – December 2008 were evaluated. Results: Mean maternal age and nulliparity rate were 27.5 ± 5.2 and 50 % respectively. In two patients (2/8, 25 %) variceal bleeding during pregnancy occured. Mean gestational week of delivery and birth weight were 35.3 ±3.3 and 2525 ± 846 gram respectively. The rates of fetal growth restriction and delivery before 34 weeks gestation were 25% and 12.5% respectively. There was no maternal mortality. Perinatal mortality rate was 12.5%. Conclusion: Pregnancies with non-cirrhotic portal fibrosis should be managed with a team approach. Our results indicate that these pregnancies managed properly have good pregnancy outcomes.
Abstract (Original Language): 
Amaç: Sirotik olmayan portal fibrozis ve portal hipertansiyon olgular›nda gebelik komplikasyonları ve sonuçlarını irdelemek. Yöntem: Anabilim Dalında Ocak 1998 - Aralık 2008 tarihleri arasında sirotik olmayan portal fibrozis ve portal hipertansiyon tanısı olan ve doğumları kliniğimizde gerçekleşen 8 gebe retrospektif olarak irdelendi. Bulgular: Olgularının ortalama maternal yaşı 27.5 ± 5.2 ve nulliparite oranı %50 olarak saptandı. İki olguda (2/8, %25), ciddi komplikasyon olarak, gebelik sırasında özefagus varis kanaması oldu. Gebelerin ortalama doğum haftası 35.3 ±3.3 ve doğum kilosu 2525 ± 846 gram olarak belirlendi. Fetal gelişim kısıtlılığı ve 34 gebelik haftası öncesi doğum oranları sırasıyla % 25 ve %12.5 olarak saptandı. Grubumuzda maternal mortalite gözlenmezken, perinatal mortalite oranımız %12.5 (1/8) olarak belirlendi. Sonuç: Sirotik olmayan portal fibrozisli olguların gebelikleri uygun yaklaşım ve ekip anlayışı işinde takip edilmelidir. Bu yaklaşım ile gebelik sonuçları genel anlamda olumludur.
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REFERENCES

References: 

Kaynaklar
1. Benhamou JP, Valla DC. Intrahepatic portal hypertension.
In: Bircher J, Benhamou JP, McIntyre N, et al,
eds. Oxford Textbook of Clinical Hepatology. 2nd ed.
Oxford: Oxford University Press, 1999. p.661–670.
2. Sar›n SK, Kapoor D. Non-cirrhotic portal fibrosis: current
concepts and management. J Gastroenterol
Hepatol 2002; 17: 526–534.
3. Okuda K. Non-cirrhotic portal hypertension: why is it
so common in India? J Gastroenterol Hepatol 2002;
17: 1–5.
4. Britton RC. Pregnancy and esophageal varices. Am J
Surg 1982;143: 421- 425.
5. Tan J, Surti, B, Saab S. Pregnancy and cirrhosis Liver
Transpl 2008; 14: 1081-1091.
6. Sumana G, Dadhwal V, Deka D, Mittal S. Non-cirrhotic
portal hypertension and pregnancy outcome. J
Obstet Gynaecol Res 2008; 34: 801-804.
7. Varma RR, Michelsohn NH, Borkowf HI, Lewis JD.
Pregnancy in cirrhotic and noncirrhotic portal hypertension.
Obstet Gynecol 1977; 50: 217–222.
8. Hermann RE, Esselstyn CB Jr. The potential hazard of
pregnancy in extrahepatic portal hypertension. Report
of two cases. Arch Surg 1967; 95: 956–959.
9. Kochhar R, Kumar S, Goel RC, Sriram PV, Goenka
MK, Singh K. Pregnancy and its outcome in patients
with noncirrhotic portal hypertension. Dig Dis Sci
1999; 44: 1356–1361.
10. Aggarwal N, Sawhney H, Vasishta K, Dhiman RK,
Chawla Y. Non-cirrhotic portal hypertension in pregnancy.
Int J Gynaecol Obstet 2001; 72: 1–7.
11. Günflar F. Gebelik ve portal hipertansiyon. Türkiye
Klinikleri J Gastroenterohepatol. (Special Topics)
2008; 1: 85-88.

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