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Ailevi Akdeniz Ateşi Hastalarında Vücut Kompozisyonunun Değerlendirilmesi

Assessment of Body Composition in Familial Mediterranean Fever

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Abstract (2. Language): 
Objective: Familial Mediterranean fever (FMF) is an autoinflammatory rheumatic disease characterized by the recurrent attacks of serositis. The aim of the present study is to examine the body composition in patients with FMF. Materials and Methods: 38 FMF patients and 31 healthy control subjects included in the study. Patients with hypertension, diabetes and hyperlipidemia were excluded. Body composition was assessed by anthropometrically (body mass index; BMI, waist circumference and waist to hip ratio), skinfold measurements and bioelectric impedance analysis (BIA) methods. Results: Age, sex distribution, smoking status, BMI, waist circumference and waist-to-hip ratios were similar between both FMF and control groups (p>0.05). Fat mass (estimated from both Siri's equation and BIA), fat free mass and total body water amounts were comparable between FMF and control groups (p>0.05). Correlation analysis revealed significant correlations between disease duration, ESR and body fat estimated from BIA (p<0.05). Siri's fat percent was significantly correlated with age disease duration and ESR (p<0.05). Total body water was also correlated with age and ESR (p<0.05). Conclusion: Our study indicated that body composition is not different in FMF patients when compared with healthy subjects
Abstract (Original Language): 
Amaç: Ailevi Akdeniz ateşi (AAA) tekrarlayan serozit ataklarıyla karakterize otoinflamatuvar bir romatizma hastalığıdır. Bu çalışmanın amacı A A A hastalarında vücut kompozisyonunun değerlendirilmesidir. Gereç ve Yöntemler: 38 A A A hastası ve 31 sağlıklı kontrol çalışmaya alındı. Hipertansiyon, diyabet ve hiperlipidemisi olan bireyler çalışma dışı bırakıldı. Vücut kompozisyonu değerlendirmesinde antropometrik ölçümler (vücut kitle indeksi; VKİ, bel çevresi, bel-kalça oranı), cilt kıvrım kalınlığı yöntemi ve biyoelektrik impedans analizi (BİA) kullanıldı. Bulgular: Hasta ve kontrollerin yaş, cinsiyet dağılımları, sigara kullanımları, VKİ, bel çevresi, bel-kalça oranları benzer özellikteydi (p>0.05). Her iki gurubun yağ yüzdeleri (gerek Siri gerekse BİA'dan hesaplanan), yağsız vücut kitleleri ve toplam vücut su miktarları arasında farklılık tespit edilemedi. Korelasyon analizinde BİA'dan elde edilen yağ yüzdesi hastalık süresi ve ESH ile anlamlı ilişki göstermekteydi (p<0.05). Cilt kıvrımlarından elde edilen yağ miktarı da (Siri%) yaş, hastalık süresi ve ESH ile ilişkiliydi (p<0.05). Toplam vücut su miktarı da yaş ve ESH ile anlamlı ilişki göstermekteydi (p<0.05). Sonuç: Çalışmamız A A A hastalarının vücut kompozisyonu parametrelerinin sağlıklı kontrollerden farklı olmadığını ortaya koymuştur.
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