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Diabetes Mellituslu Hastalarda 24 Saatlik, Anlık ve Gecelik İdrarlarda Mikroalbumin Ölçümü

Measurements of Microalbumin in Urine Samples of 24 Hours, Spot and Nightly in Patients with Diabetes Mellitus

Journal Name:

  • Fırat Tıp Dergisi

Publication Year:

  • 2010

Key Words:

Keywords (Original Language):

Author NameUniversity of Author
Abstract (2. Language): 
Objective: We aimed to investigate i f the nightly urine samples can be used instead of spot urine samples and 24 hour urine samples which are uncomfortable for patients, by comparing nightly urine samples with 24 hour and spot urine samples. Materials and Methods: Urine samples were collected for 24 hours, spot, nightly for the measurement microalbuminuria in sixty patients (32 men, 28 women) with diabetes mellitus. Patients with urinary 38 oC), and evidence of chronioinfection, evidence of pregnancy, fever (disease were excluded from this study. Results: Microalbuminuria was determined 28% of urine samples of 24 hours, 72% of spot urine samples, 58% calculation of the albumin/creatinine ratio in spot urine samples, 93 % of nightly urine samples. Conclusion: We suggest that the measurement of microalbuminuria in nightly urine samples which are less affected than the other collection methods (24 hour and spot urine samples) for the factors such as hydration, physical activity and collection errors, to be more sensitive
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Abstract (Original Language): 
Amaç: Gecelik idrar örneklerinde mikroalbümin ölçümü 24 saatlik ve anlık idrar örnekleriyle kıyaslanarak, hastalar için konforsuz bulunan 24 saatlik idrar yerine kullanılıp kullanılmayacağı araştırıldı. Gereç ve Yöntemler: Çalışmaya 24 saatlik idrarda mikroalbümin isteği olan ve yapılan sorgulamalar sonucunda diabetes mellitus tanısı dışında kronik bir hastalık, gebelik, son iki gün içinde ağır egzersiz, idrar yolu enfeksiyonu ve ateşi olanlar hariç 32'si erkek olmak üzere toplam 60 hasta alındı. Bulgular: 24 saatlik idrar örneklerinin %28'inde, anlık idrar örneklerinin %72'sinde, kreatininle düzeltilmiş anlık idrar örneklerinin %58'inde ve gecelik idrar örneklerinin %93'ünde mikroalbüminüri tespit edildi. Sonuç: Hastaların örnek toplamadaki hatalarının en aza indirgendiği ve hidrasyon, fiziksel aktivite gibi çeşitli faktörlerden en az etkileneceğini dü¬ şündüğümüz gecelik idrar numunelerinde mikroalbümin ölçümünün daha hassas bir yöntem olacağını önermekteyiz.
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  • 2
92-95
  • Turkish

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