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Büyüme geriliği sebebi olarak renal tübüler asidozlu bir olgu sunumu

Renal tubular acidosis causing growth retardation: a case presentation

Journal Name:

  • Gülhane Tıp Dergisi

Publication Year:

  • 2006

Key Words:

Keywords (Original Language):

Author Name
Abstract (2. Language): 
Renal tubular acidosis is a condition resulting from a defect in either hydrogen excretion or bicarbonate reabsorption from renal tubuli. Renal tubular acidosis may present with hypocalcemia, medullar nephrocalcinosis, recurrent calcium phosphate stones, growth retardation and rickets in children. Renal tubular acidosis type I is characterized with failure to lower urinary pH and metabolic acidosis, due either to excessive backdiffusion of hydrogen ions from the lumen or to inadequate excretion of hydrogen ions. Alkaline urine and metabolic acidosis with normal anion gap were detected in a ten-month-old patient admitted with the complaints of growth failure and vomiting. Nephrocalcinosis, calcium phosphate stones and rickets were detected on radiological and laboratory investigations. Alkali treatment was started with the diagnosis of renal tubular acidosis type I.
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Abstract (Original Language): 
Renal tübüler asidoz, tübülüslerde hidrojen iyonunun atılımında veya bikarbonatın emilimindeki defekt sonucu ortaya çıkan bir tablo olup, çocuklarda hipokalemi, medüller nefrokalsinozis, rekürren kalsiyum fosfat taşları, büyüme geriliği ve raşitizm bulguları ile ortaya çıkabilir. Renal tübüler asidoz tip I, distal tübülüslerde lümenden fazla miktarda hidrojen iyonunun geri difüzyonuna veya yetersiz hidrojen iyon atılımına bağlı olarak metabolik asidoz ve idrar pH'ının düşürülememesi ile karakterizedir. Büyüme geriliği ve kusma şikayeti ile başvuran on aylık hastada alkali idrar ve normal anyon açığına eşlik eden metabolik asidoz saptandı. Radyolojik ve laboratuvar olarak nefrokalsinozis, kalsiyum fosfat taşları ve raşitizm saptandı. Hastaya renal tübüler asidoz tip I tanısı konularak alkali tedavisi başlandı.
FULL TEXT (PDF): 
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  • 4
236-238
  • Turkish

REFERENCES

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