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Akciğer tümörünü taklit eden toraks yerleşimli nörofibroma: olgu sunumu

Neurofibroma in the thorax mimicking lung tumor: case report

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Abstract (2. Language): 
Neurofibroma is a neurogenic tumor in the peripheral nerve tumor group. A 25-year-old male patient without any complaints hospitalized due to a probable peripheral lung tumor is presented in this article. Thorax computed tomography was performed to identify a 4 cm round mass lesion in the posterior mediastinal compartment detected on chest radiograms and revealed a peripheral lung tumor causing vertebral destruction. The patient had no pathologic signs on physical examination, and bronchoscopic examination and computed tomography guided transthoracic needle aspiration revealed no specific diagnosis. Further investigation by magnetic resonance imaging demonstrated a nerve sheath tumor. Lateral thoracotomy was performed, the paraspinal mass at the level of T4-T7 vertebra was removed surgically, and histopathological diagnosis was neurofibroma. Neurofibroma should be considered in the differential diagnosis when a tumor is detected in the posterior mediastinal location. Surgery is the main therapeutic approach in this type of tumors.
Abstract (Original Language): 
Nörofibroma periferal sinir tümörleri grubu içinde yer alan nörojenik bir tümördür. Bu makalede herhangi bir yakınması olmayan, akciğer radyogramında arka mediyastinal kompartmanda 4 cm çaplı yuvarlak kitle lezyonu görülmesi üzerine gerçekleştirilen toraks bilgisayarlı tomografi incelemesinde, vertebra harabiyetine sebep olduğu düşünülen periferik akciğer tümörü ön tanısı ile ileri tetkik için hastanemize yatırılan 25 yaşında bir erkek hasta sunulmuştur. Fizik muayenesinde patolojik bulgu olmayan, bronkoskopik inceleme ve transtorakal iğne aspirasyonu ile tanı konulamayan hastanın, manyetik rezonans görüntüleme incelemesi sonucunda, sinir kılıfı tümörü olduğu düşünüldü. Lateral torakotomi ile çıkarılan T6-T7 vertebra seviyesindeki paraspinal kitlenin histopatolojik incelemesi sonucu nörofibroma tanısı kondu. Arka mediyasten yerleşimli bir tümör tespit edildiğinde, nörofibroma ayırıcı tanıda düşünülmelidir. Bu tür tümörlerde asıl tedavi cerrahidir.
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REFERENCES

References: 

1. Azarow KS, Pearl RH, Zurcher R, Edwards FH, Cohen
AJ. Primary mediastinal masses. J Thorac Cardiovasc Surg
1993; 106: 67-72.
2. Wychulis AR, Payne WS, Clagett OT, Woolner LB.
Surgical treatment of mediastinal tumors. J Thorac
Cardiovasc Surg 1971; 62: 379-391.
3. Davis RD, Oldham HN, Sabistan DC. Primary cysts and
neoplasms of the mediastinum: recent changes in clinical
presentation, methods of diagnosis, management and
results. Ann Thorac Surg 1987; 44: 229-237.
4. Shields TW, Reynolds M. Neurogenic tumors of the thorax. Surg Clin North Am 1988; 68: 645-668.
5. Hoffman OA, Gillespie DJ, Aughenbaugh GL, Brown
LR. Primary mediastinal neoplasms (other than thymomas). Mayo Clin Proc 1993; 68: 880-891.
6. Swanson PE. Soft tissue neoplasms of the mediastinum.
Semin Diagn Pathol 1991; 8: 14-34.
7. Strollo DC, Rosado de Christensenson ML, Jett JR.
Primary mediastinal tumors. Part II. Tumors of the midd-Cilt 49 · Sayý 3 · Gülhane TD Toraks yerleþimli nörofibroma · 203
le and posterior mediastinum. Chest 1997; 112: 1344-
1357.
8. Lee JY, Lee KS, Han J, et al. Spectrum of neurogenic
tumors in the torax: CT and pathologic findings. J
Comput Assist Tomogr 1999; 23: 399-406.
9. Kumar A, Kumar S, Aggarwal S, Khilnani GC.
Thoracoscopy: the preferred approach for the resection of
selected posterior mediastinal tumors. J Laparoendosc
Adv Surg Tech 2002; 12: 345-353.
10. Kelemen JJ 3rd, Naunheim KS. Minimally invasive
approaches to mediastinal neoplasms. Semin Thorac
Cardiovasc Surg 2000; 12: 301-306.
11. Canvasser DA, Naunheim KS. Thoracoscopic management of posterior mediastinal tumors. Chest Surg Clin N
Am 1996; 6: 53-67.
12. Pun YW, Moreno Balsalobre R, Prieto Vicente J,
Fernandez Fau L. Multicenter experience of video-assisted thoracic surgery to treat mediastinal cysts and tumors.
Arch Bronchopneumol 2002; 38: 410-414.
13. Hazelrigg SR, Boley TM, Krasna MJ, Landreneau RJ, Yim
AP. Thoracoscopic resection of posterior neurogenic
tumors. Am Surg 1999; 65: 1129-1133.
14. Venissac N, Leo F, Hofman P, Paquis P, Mouroux J.
Mediastinal neurogenic tumors and video-assisted thoracoscopy: always the right choice. Surg Laparosc Endosc
Percutan Tech 2004; 14: 20-22.
15. Zhang Z, Zhou Y, Cui Y, et al. Diagnosis and surgical
management of mediastinal neurogenic tumors.
Zhonghua Wai Ke Za Zhi 2002; 40: 676-678.
16. Topcu S, Alper A, Gulhan E, Kocyigit O, Tastepe I, Cetin
G. Neurogenic tumours of the mediastinum: a report of
60 cases. Can Respir J 2000; 7: 261-265.
17. Schemezer A, Reinosch W, Laqua D, Bahr R. Thoracic
neurinoma: a rare tumor of the posterior mediastinum.
Chirurg 1996; 67: 90-92.
18. Zhang H, Ping Y, Bai S. Clinicopathological characteristics and surgical treatment of primary neurogenic tumors
of the mediastinum. Zhonghua Zhong Liu Za Zhi 1999;
21: 458-460.
19. Yuksel M, Pamir N, Ozer F, Batirel HF, Ercan S. The
principles of surgical management in dumbbell tumors.
Eur J Cardiothorac Surg 1996; 10: 569-573.

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