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Hiperkalsemi nedeni ile başvuran bir çocukta nadir bir neden: akut lenfoblastik lösemi

An unusual diagnosis in a child presenting with hypercalcemia: acute lymphoblastic leukemia

Journal Name:

  • Gülhane Tıp Dergisi

Publication Year:

  • 2010

Key Words:

Keywords (Original Language):

Author Name
Abstract (2. Language): 
Hypercalcemia is a rare complication of acute lymphoblastic leukemia in childhood. We report a 4-year-old boy who presented with hypercalcemia and was diagnosed to have acute leukemia. The laboratory tests for main causes of hypercalcemia (Hyperparathyroidism, hypervitaminosis A and D, hyperthyroidism) were within normal limits. Hypercalcemia was treated with intravenous isotonic sodium chloride solution, furosemide and corticosteroids. In repeat laboratory tests performed on day 4 of admission, a normal complete blood cell count was found, but peripheral blood smear examination at this time revealed atypical lymphocytes. A bone marrow aspiration was performed, and 80% lymphoblasts were determined. The diagnosis of acute leukemia cannot be excluded in a patient with hypercalcemia and normal complete blood cell count and peripheral blood smear examination results. Repeat laboratory and detailed peripheral blood smear examinations are necessary to make a correct diagnosis in such cases.
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Abstract (Original Language): 
Hiperkalsemi çocukluk çağı akut lenfoblastik lösemilerinde nadir bir komplikasyondur. Bu yazıda hiperkalsemi ile başvuran ve akut lösemi tanısı konulan 4 yaşında bir erkek olgu sunulmuştur. Hiperkalseminin ana nedenlerine (hiperparatroidi, vitamin A veya D aşırı alımı, hipertiroidizm) yönelik laboratuvar testler normal bulundu. Hiperkalsemi, intravenöz izotonik sodyum klorür, furosemid ve steroidler ile tedavi edildi. İzleminin dördüncü gününde tekrarlanan laboratuvar testlerinde tam kan sayımı normal olarak bulundu, fakat periferik yayma incelemesinde atipik lenfositler tespit edildi. Yapılan kemik iliği aspirasyon incelemesinde %80 oranında lenfoblast belirlendi. Tam kan sayımı ve periferik yayma incelemesinin normal olduğu hiperkalsemili bir hastada akut lösemi tanısı ekarte edilemez. Böyle olgularda laboratuvar tetkiklerinin ve periferik yayma incelemelerinin tekrarlanması doğru tanı koyma açısından önemlidir.
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  • 1
47-48
  • English

REFERENCES

References: 

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