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Yaşlı erkeklerde osteoporoz risk faktörlerinin değerlendirilmesi

Analysis of risk factors in older men with osteoporosis

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Abstract (2. Language): 
There is little information regarding the risk factors of osteoporosis in older men. The aim of this study was to examine the risk factors in older men with osteoporosis. Medical records of 209 older men (mean age: 77.1±6.0 years) who admitted to the Geriatric Clinics of Gulhane Military Medical Academy were examined prospectively. The measurement of bone mineral density was made at the lumbar spine and femur by the DEXA method. Osteoporosis and osteopeny were observed in 64 (30.6%) and 92 (44.0%) of the 209 cases, respectively. Bone mineral density was normal in 53 (25.4%) cases. The last ten-year history revealed fracture in 25 (11.6%) osteoporotic and 14 (6.7%) osteopenic cases. Osteoporosis was more common in those with lower body mass index scores (p<0.05). The incidence of osteoporosis was higher in those who were not making exercise (p<0.05). Age, waist circumference, erythrocyte sedimentation rate, and the levels of ionized calcium, magnesium, phosphor and thyroid stimulating hormone were not related with osteoporosis (p>0.05). In our study it was detected that osteoporosis was less prevalent in older men who had higher body weight index scores and regular physical activity. The results indicate that the primary prevention with exercise and good nourishment is an important factor in preserving bone mineral density in men older than 65 years just as in adults and young subjects.
Abstract (Original Language): 
Yaşlı erkeklerdeki osteoporoz risk faktörleri ile ilgili bilgiler literatürde sı- nırlıdır. Bu çalışmanın amacı, erkek geriatrik bireylerdeki osteoporoz risk faktörlerini incelemekti. Gülhane Askeri Tıp Akademisi Geriatri polikliniğine başvuran 209 yaşlı erkek olgunun (ortalama yaş: 77.1±6.0 yıl) tıbbi verileri ileriye dönük olarak incelendi. Kemik mineral yoğunluğu ölçümü DEXA yöntemi ile lomber omur ve femurda yapıldı. Bunlar içinde 64 (%30.6) olguda osteoporoz, 92’sinde (%44.0) osteopeni saptandı. Elli üç (%25.4) olguda kemik mineral yoğunluğu normal sınırlar içerisindeydi. Geçmiş 10 yıllık sü- rede osteoporotik 25 (%11.6) olguda, osteopenik 14 (%6.7) olguda kırık öyküsü olduğu öğrenildi. Vücut kitle indeksi düşük olanlarda osteoporoz daha yaygındı (p<0.05). Egzersiz yapmayanlarda osteoporoz insidansı daha yüksekti (p<0.05). Yaş, bel çevresi, eritrosit sedimantasyon hızı, iyonize kalsiyum, magnezyum, fosfor ve tiroid stimüle edici hormon düzeyi osteoporoz ile ilişkili değildi (p>0.05). Çalışmamızda vücut kitle indeksi yüksek olan ve düzenli egzersiz yapan yaşlı erkeklerde osteoporozun daha az gö- rüldüğü tespit edilmiştir. Sonuçlar erişkin ve gençlere benzer şekilde, 65 yaş üstü erkeklerde birincil önlemede egzersizin ve iyi beslenmenin kemik mineral yoğunluğunu korumada önemli faktörler olduğunu göstermektedir.
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REFERENCES

References: 

Kaynaklar
1. Randell A, Sambrook PN, Nguyen TV, et al. Direct
clinical and welfare costs of osteoporotic fractures in
elderly men and women. Osteoporosis Int 1995; 5:
427-432.
2. Gilbert SM, McKiernan JM. Epidemiology of male
osteoporosis and prostate cancer. Curr Opin Urol 2005;
15: 23-27.
3. The National Osteoporosis Foundation (NOF) Clinician’s
Guide to prevention and treatment of osteoporosis
2008. National Osteoporosis Foundation, Washington,
DC. Website: http://www.nof.org/professionals/NOF_
Clinicians_Guide.pdf
4. Kelly TL Sp, von Stetton E. Performance evaluation of
a multi-detector DXA device. J Bone Miner Res 1991; 6:
168.
5. Villareal DT, Shah K, Banks MR, Sinacore DR, Klein
S. Effect of weight loss and exercise therapy on bone
metabolism and mass in obese older adults: A one-year
randomized controlled trial. J Clin Endocrinol Metab
2008; 93: 2181-2187.
6. Boyanov M, Bakalov D, Boneva Z. Bone mineral density
in men with and without the metabolic syndrome.
Aging Male 2009; 12: 62-65.
7. Fu X, Ma X, Lu H, He W, Wang Z, Zhu S. Associations
of fat mass and fat distribution with bone mineral
density in pre- and postmenopausal Chinese women.
Osteoporos Int 2010 Mar 20 [Epub ahead of print].
8. Yang LF, Xie H, Yuan LQ. Serum adiponectin and leptin
levels and bone mineral density in 232 men. Zhong
Nan Da Xue Xue Bao Yi Xue Ban 2008; 33: 523-526.
9. Rowe GC, Soo Choi C, Neff L, Horne WC, Shulman
GI, Baron R. Increased energy expenditure and insulin
sensitivity in the high bone mass ∆FosB transgenic
mice. Endocrinology 2009; 150: 135-143.
10. Vondracek SF, Linnebur SA. Diagnosis and management
of osteoporosis in the older senior. Clin Interv Aging
2009; 4: 121-136.
11. Karlsson MK, Nordqvist A, Karlsson C. Physical activity, Cilt 52 • Sayı 3 Osteoporoz risk faktörleri • 171
muscle function, falls and fractures. Food Nutr Res
2008; 52. DOI: 10.3402/fnr.v52i0.1920.
12. Tüzün Ş, Aktaş İ, Akarırmak Ü, Sipahi S, Tüzün F. Yoga
might be an alternative training for the quality of life
and balance in postmenopausal osteoporosis. Eur J Phys
Rehabil Med 2010; 46: 69-72.
13. Angın E, Erden Z. The effect of group exercise on
postmenopausal osteoporosis and osteopenia. Acta
Orthop Traumatol Turc 2009; 43: 343-350.
14. Kanis JA. Diagnosis of osteoporosis and assessment of
fracture risk. Lancet 2002; 359: 1929-1936.
15. Barrett-Connor E, Nielson CM, Orwoll E, Bauer DC,
Cauley JA. Epidemiology of rib fractures in older men:
Osteoporotic Fractures in Men (MrOS) prospective
cohort study. BMJ 2010; 340: c1069.
16. Korkor AB, Eastwood D, Bretzmann C. Effects of
gender, alcohol, smoking, and dairy consumption on
bone mass in Wisconsin adolescents. WMJ 2009; 108:
181-188.
17. Oncken C, Prestwood K, Kleppinger A, Wang Y, Cooney
J, Raisz L. Impact of smoking cessation on bone mineral
density in postmenopausal women. J Womens Health
2006; 15: 1141-1150.
18. Stránský M, Ryšavá L. Nutrition as prevention and
treatment of osteoporosis. Physiol Res 2009; 58: 7-11.
19. Hippisley-Cox J, Coupland C. Predicting risk of
osteoporotic fracture in men and women in England
and Wales: prospective derivation and validation of Q
fracture Scores. BMJ 2009; 339: b4229.
20. Duncan Bassett JH, O’Shea PJ, Sriskantharajah S, Rabier
B, Boyde A, Howell PGT. Thyroid hormone excess rather
than thyrotropin deficiency induces osteoporosis in
hyperthyroidism. Mol Endocrinol 2007; 21: 1095-1107.
21. Boersma B, Otten BJ, Stoelinga GB, Wit JM. Catch-up
growth after prolonged hypothyroidism. Eur J Pediatr
1996; 155: 362-367.
22. Rivkees SA, Bode HH, Crawford JD. Long-term growth
in juvenile acquired hypothyroidism: the failure to
achieve normal adult stature. N Engl J Med 1988; 318:
599-602.
23. Wang Y, Wu H, Zhou J. Post-thyroidectomy osteoporosis.
Zhonghua Zhong Liu Za Zhi 1996; 18: 308-309.

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