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DAYANIKLILIK ANTRENMANLARINDA ANTİOKSİDAN SAVUNMA

ANTIOXIDANT DEFENSE IN THE ENDURANCE TRAINING ABSTRACT

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Abstract (2. Language): 
The presented study was planned in order to investigate the effects of endurance training on erythrocyte superoxyde dismutase (SOD) and catalase (CAT) enzyme activities and plateled malondialdehit (MDA) level. 14 healthy, sedentary volunteers, aged 18-21 years, participated in the study The participants were performed 30 minutes of submaximal exercise with a load corresponding to 75 % maximal heart rate three times a week during 6 weeks. Blood samples were obtained before and after the exercises that performed at the first, 3rd and 6th week of the training. Erythrocyte SOD, CAT enzyme activities and plateled MDA levels were measured. The results were evaluated statistically by paired t test. Erythrocyte SOD enzyme activity increased after the exercise at the 3rd and 6th week (p<0.05). Eryhrocyte CAT enzyme activities and plateled MDA levels did not change. The results show that the endurance training has increasing effect on the first stage of the antioxidant enzymatic defense.
Abstract (Original Language): 
Dayanıklılık antrenmanının eritrosit süperoksit dismutaz (SOD), katalaz (CAT) enzim aktiviteleri ve trombosit malondialdehit (MDA) düzeyi üzerine etkisini araştırmak amacıyla programlanan çalışmaya, 18-21 yaşlan arasında 14 gönüllü, sağlıklı, sedanter katıldı. Denekler 6 hafta süreyle, haftada 3 kez, maksimal kalp atım sayısının %75'ine karşılık gelen yükle 30 dakika süren bir egzersiz programına alındı. Programın başında, deneklerde eritrosit SOD, CAT aktivitesini ve trombosit MDA düzeyini saptamak üzere kan alındıktan 20 dakika sonra ilk egzersiz yaptırıldı, ilk egzersizden sonra 3 ve 6 haftalık antrenman sonunda egzersizden önce ve sonra kan alınarak eritrosit SOD, CAT aktivitesi ve trombosit MDA düzeyi saptandı. Sonuçlar eşleşmiş t testi ile istatistiksel olarak değerlendirildi. 3. ve 6. Hafta sonunda eritrosit SOD aktivitesinde anlamlı artış (p<0.05) saptanırken, eritrosit CAT aktivitesi ve trombosit MDA düzeyinde değişiklik olmadı. Çalışmadan elde edilen sonuçlar, dayanıklılık antrenmanlarının antioksidan enzimatik savunmanın özellikle birinci basamağında güçlendirici bir etkiye sahip olduğunu gösterdi.

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