You are here

Home » Content

Prevalence Of Osteoporosis In Relation To 10 Years Probability Of Major Osteoporotic Fracture And Hip Fracture Risk Using Country Specific Frax Algorithm In Postmenopausal Women In India

Journal Name:

  • Indian Streams Research Journal

Publication Year:

  • 2013

Key Words:

Author Name
Abstract (2. Language): 
The purpose of the study was to investigate the prevalence of osteoporosis in relation to assess the 10-year probability percentage of Major Osteoporotic Fracture Risk and to assess the10-year probability percentage of Hip Fracture Risk using FRAX country specific algorithm with bone mineral density. Method: 74 older osteoporotic postmenopausal females ranging the age between 40 to 90 years were randomly selected as the subject of the study. Bone mineral density T-score were obtained by using Ultrasound Bone Densitometry (Omnisense) at distal radius by the experts and technicians. WHO Fracture Risk Assessment Tool (FRAX) INDIA was used to assess the fracture risk probability. FRAX probability calculated with distal radius Bone mineral density was obtained by reference method. Results: There were significant relationship between Body mass index and Bone mineral density. The correlation was highly significant between Bone mineral density and Major Osteoporotic Fracture Risk as well as Bone mineral density and Hip Fracture Risk. Conclusion: The results provide a framework which enhances the assessment of fracture risk in women in combination with Bone mineral density. Fracture risk feedback based on Bone mineral density could potentially make an important contribution to osteoporosis prevention and treatment in postmenopausal women irrespective of age and BMI.
Bookmark/Search this post with
FULL TEXT (PDF): 
PDF icon arastrmx_177287_3_pp_1-4.pdf
  • 7
1-4
  • English

REFERENCES

References: 

1.Strom O, Borgstrom F, Kanis John A, Compston J, Cooper
C, McCloskey V E, Jonsson B, Osteoporosis: burden, health
care provision and opportunities in the EU. Arch Osteoporos,
6:59–155 (2011)
2.Kanis JA, on behalf of the World Health Organization
Scientific Group (2008) Assessment of osteoporosis at the
primary healthcare level. Technical report. WHO
Collaborating Centre, University of Sheffield, UK. Available
at http://www.shef.ac.uk/FRAX/index.htm
3.Marshall D, Johnell O, Wedel H: Meta-analysis of how
well measures of bone mineral density predict occurrence of
osteoporotic fractures. BMJ,; 312:1254–1259 (1996)
4.Cummings SR, Melton LJ: Epidemiology and outcomes of
osteoporotic fractures. Lancet,; 359:1761–1767.( 2002)
5.Siris ES, Chen YT, and Abbott TA. Bone mineral density
thresholds for pharmacological intervention to prevent
fractures. Arch Intern Med,; 164:1108–1112 (2004)
6.Cauley JA, Wu L, Wampler NS. Clinical risk factors for
fractures in multi-ethnic women: the Women's Health
Initiative. J Bone Miner Res,; 22:1816–1826.( 2007)
7.Joop P. W. van den Bergh, Tineke A. C. M. van Geel,
Willem F. Lems, Piet P. Geusens. Assessment of Individual
Fracture Risk: FRAX and Beyond. Curr Osteoporos Rep,;
8:131–137( 2010)
8.Kanis JA: Diagnosis of osteoporosis and assessment of
fracture risk. Lancet,2002; 359:1929–1936.
9.Roux C, Reginster JY, Fechtenbaum J. Vertebral fracture
risk reduction with strontium ranelate in women with postmenopausal
osteoporosis is independent of baseline risk
factors. J Bone Miner Res,;21:536–542 (2006)

Thank you for copying data from http://www.arastirmax.com