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Aflatoksin Bı'in tavşanlarda bazı kan parametreleri üzerindeki etkisi

Effects of aflatoxin Bt on some blood parameters in the rabbits

Journal Name:

  • İnönü Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 1994

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
In this study, 30 male rabbits belong to New Zeland strain (Oryctolagus cuniculus huxleyi) were used. The rabbits were groupped as A, B, C and 0.005, 0.00~5 and 0.010 mgr kg day aflatoxin Bj was given respectively. The data was analysed with two-way ANOIA and correlation A NOVA. It was found that the number of leucocyte and erythrocyte, the value of hematocrit and also the average hemoglobin value of a single erythrocyte changed istatisticaly depending on the groups measurements interval and interactions. Hemoglobin value and the number of platelet showed imfxirtant differences between measurements in time only. The average volume of a single erythrocyte showed differences between experimentals groups only. In the spite of these differences, for all groups given aflatoxin Bt the negative relationship were observed between number of platelet, hematocrit value in time. It was also found that there is a positive relationship between the number of leucocyte, hemoglobin value and the average hemoglobin value of a single erythrocyte in time. On the other hand, the number of erythrocyte, the average volume of a single erythrocyte and the average hemoglobin concentration of a single erythrocyte exhibits a positive relationship for some groups and a negative for the other groups in time. The data were compared with literature and discussed. /Journal of Turgut Özal Medical Center 1(2): 93-103 ,1994/
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Abstract (Original Language): 
Çalışmada, Yeni /elanda ırkı (Oryctolagus cuniculus huxleyi) 30 erkek tavşan kullanıldı. Tavşanlar gruplandırıldı ve deneklerin A grubuna 0.005, Bgrubuna 0.0075 ve Cgrubuna 0.010 mgr/kg/gün aflatoksin B, verildi, feriler çift yönlü varyans ve korelasyon analizine tabi tutuldu. Lökosit, eritrosit sayıları, hemalokrit değeri ve tek bir eritrositin ortalama hemoglobin değeri (MCH) deneme grupları, ölçümler arası ve etkileşim bakımından istatistiksel olarak önemli farklar gösterdi. Hemoglobin değeri ve trombositlerin sayısı sadece ölçümler arası bakımından istatistiksel olarak önemli farklılıklar gösterirken tek bir eritrositin ortalama hacim (MCf) değerleri deneme grupları arasındaki değer yönünden farklılık gösterdi. Bu farklılıklara karşın aflatoksin B, verilen bütün gruplarda zaman içerisinde trombosit sayısı ve hematolcrit değerinde negatif, lökosit sayısı, hemoglobin değeri ve tek bir eritrositin ortalama hemoglobin değerinde (MCH) ise başlangıca göre pozitif bir ilişki saptandı. Eritrosit sayısı, tek bir eritrositin ortalama hacmi (MCf) ve tek bir eritrositin ortalama hemoglobin konsantrasyonunda (MCHC) zaman içerisinde bazı gruplarda pozitif, bazı gruplarda negatif bir ilişki görüldü. \ 'eriler literatür ile karşılaştırıldı ve tartışıldı. /Turgut Özal Tıp Merkezi Dergisi l(2):93-103,1994f
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93-103
  • Turkish

REFERENCES

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