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Hemodiyalize giren ve girmeyen kronik böbrek yetmezliği olan hastalarda lipit profilleri

Lipid profiles in hemodialysis and nonhemodialysis patients with chronic renal insufficiency

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Abstract (2. Language): 
In this study, plasma concentrations of total cholesterol (TC), triglycerides (TG), high density lipoprotein cholesterol (FfDL-C), low density li/xtprotein cholesterol (LDL-C). apolipoprotein A-I (Apo A-l) and B (Apo B). and the ratios of HDL-C to TC, HDL-C to LDL-C and Apo A-I to Apo B in 38 hemodialysis and 30 predialysis patients were compared with the concentrations and ratios in 34 healthy subjects.The highest plasma TC. HDL-C TC . HDL-C/ LDL-C, and Apo A-T Apo B ratios in both of the patient gruops. As a result, these data show that patients who undergo regular hemodialysis show tendency of atherosclerotic disease development. [Journal of Turgut (hal Medical Center 1(3): 194-197,1994]
Abstract (Original Language): 
Bu çalışmada, 38 hemodiyaliz ve 30 prediyaliz hastasında plazma total kolesterol (TC), trigliseritler (TG), yüksek dansiteli lipoprotein kolesterol (HDL-C), düşük dansiteli lipoprotein kolesterol (LDL-C), apolipoprotein A-l (Apo A-I), apolipoprotein B (Apo B) konsantrasyonları ile HDL-C"nin TC'ye, HDL-C nin LDL-C ye ve Apo A-I 'in Apo B 'ye olan oranları 34 sağlıklı kişinin plazma konsantrasyonları ve oranları ile karşılaştırıldı. Hemodiyaliz hastalarında plazma TC, HDL-C ve Apo A-l daha düşük ancak plazma TG 'i daha yüksek olarak tespit edildi. Kontrollerle karşılaştırılınca HDL-C TC. HDL-C/LDL-C ve Apo A-I/Apo B oranlarının her iki hasta grubunda da anlamlı farklılık vardı. Sonuç olarak, bu verilere göre düzenli hemodiyalize giren hastalarda aterosklerotik hastalık gelişme riski vardır. {Turgut Özal Tıp Merkezi Dergisi 1(3): 194-İT. 1994]
194-197

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