You are here

Home » Content

Doğurganlık Çağındaki Kadınlarda Rubella ve Sitomegalovirus Antikorlarının Araştırılması

Screening Of Antıbodies Against Cytomegalovirus and Rubella Virus In Childbearing Age's Women

Journal Name:

  • İnönü Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 2003

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Objective: In this study, incidence of rubella and CMV antibodies have been investigated in risk groups including childbearing age's women. Material and Methods: IgM and IgG antibodies against Cytomegalovirus and Rubella were tested by ELISA (Organon) kits. Results: While rubella IgM antibodies was found positive in 0.3% percent of tested serum samples, positivity for rubella IgG antibodies was 88%. The positivities of the serum samples for CMV IgM and CMV IgG were 0.4% and 94%, respectively. Conclusions: It was concluded that susceptible candidates of pregnancy should be educated about prevention and control of CMV and rubella infections and that following up the patients can decrease the risk of congenital abnormalities.
Bookmark/Search this post with
Abstract (Original Language): 
Amaç: Çalışma, risk grubunu oluşturan doğurganlık çağındaki kadınlarda Rubella ve Sitomegalovirus antikorlarının insidansını belirlemek amacıyla yapıldı. Materyal ve Metod: Sitomegalovirus ve Rubella infeksiyonlarına karşı gelişen IgM ve IgG antikorları ELISA (Organon) kitleri kullanılarak incelenmiştir. Bulgular: İncelenen serum örneklerinde %0.3 oranında rubella IgM pozitifliği saptanırken; Rubella IgG %88 oranında belirlendi. CMV IgM ve CMV IgG için ise sırasıyla %0.4 ve %94 oranında pozitiflik gözlendi. Sonuç: Duyarlı anne adaylarının CMV ve Rubella infeksiyonlarından korunma ve kontrol konusunda eğitilmeleri ve takiplerinin doğumsal anomali riskini azaltacağı kanısına varıldı.
FULL TEXT (PDF): 
PDF icon arastirmax-dogurganlik-cagindaki-kadinlarda-rubella-sitomegalovirus-antikorlarinin-arastirilmasi.pdf
  • 3
129-131
  • Turkish

REFERENCES

References: 

1. Stegmann BJ, Carey JC. TORCH Infections. Toxoplasmosis, other (syphilis, varicella-zoster, parvovirus B19), Rubella, Cytomegalovirus (CMV), and Herpes infections. Curr Womens Health Rep 2002; 2(4): 253-8.
2.Akan E. Genel ve Özel Viroloji, 3. baskı. İzmir: Saray Medikal yayıncılık, 1994: 113-5.
3. Davis B, Dulbecco R Eisen HN, Ginsberg HS. Microbiology. 4th ed. Philadelphia: JB Lippincott Co, 1990: 1067-74.
4. Ho M. Cytomegalovirus. In: Mandell GL, Douglas RG, Bennett JE, (eds). Principles and Practice of Infectious Disease. 3rd ed. New York, Churchill Livingstone, 2000:
1586-96.
5. Gwendolyn L Gilbert. Infections in pregnant women. The Medical Journal of Australia 2002; 176(5): 229-36.
6. Wiesenfeld HL, Sweet Rl. Perinatal infections. In: Scott JR, Disaia PJ, Hammond CB, Spellacy WIN, (eds). Danforth's Obstetrics and Gynecology. 7th ed. Philadelphia: JB
Lippincott Co, 1994: 481-2.
7. Ho M. Epidemiology of Cytomegalovirus infections. Rev Infect Dis 1990; 12: 701.
8. Pass RF. Epidemiology and transmission of Cytomegalovirus. J Infect Dis 1985: 152:
243.
9. Hizel S, Parker S, Onde U. Seroprevalence of cytomegalovirus infection among
children and females in Ankara, Turkey, 1995. Pediatr Int 1999; 41(5): 506-9 .
10. Gershon AA. Rubella virus. In: Mandell GL, Douglas RG, Bennet JE (eds). Principles and Practice of Infectious diseases. 5th ed. New York: Churchill Livingstone, 2000:
1708-12.
11.
Doğa
n N, Akgün Y. Düşük, ölü doğum, erken doğum öykülü doğurganlık yaş grubu hastalarda TORCH etkenlerinin dağılımı. Türkiye Parazitoloji Derg. 1996; 20 (3): 317¬23.
12. Erbaş O, Acar N, Önder U. Doğurgan yaş gruplarında rubella IgG antikorlarının araştırılması. XXVI. Türk Mikrobiyoloji Kongresi, Antalya.1994: 27.
13. Guner H, Gunay A, Rota S. Seroprevalence of rubella virus in Turkish pregnant
women. Int J Gynaecol Obstet 1994; 44(2): 139-41.
14. Skueri D, Head JL, Garland JM. Detection of rubella specific immunglobulin G. J
Clin Microbiol 1991; 29:1752-3.
15. Massaund M, ET Tuqui M, Saleh W. Detection of rubella virus IgG and IgM in
umblical cord sera Saudi Arabia. J Egypt Pub Hlth Assoc 1992; 66: 387-95
16. Pebody RG, Edmunds WJ, Conyn-van Spaendonck M, Olin P, Berbers G, Rebiere I, Lecoeur H, Crovari P, Davidkin I, Gabutti G, Gerike E, Giordano C, Hesketh L, Plesner AM, Raux M, Rota MC, Salmaso S, Tischer A, Valle M, Miller E. The seroepidemiology of rubella in western Europe. Epidemiol Infec 2000; 125(2): 347¬57.
17. Stagno S, Tinker MK, Elrod C, Fuccillo DA, Cloud G, O'Beima A. Immunglobulin
M antibodies detected by enzyme-linked immunosorbent assay and radioimmunoassay in the diagnosis of Cytomegalovirus infection in pregnant woman and newborn infants. J Clin Microbiol 1985; 21: 930.
18. Hayvard AR, Herberger NJ, Groothuis J, Levin MR. Specific immunity after congenital or neonatal infection with Cytomegalovirus or Herpes simplex virus. J
Immunol 1984; 133: 2469.
19. Kaleli B, Kaleli İ, Aktan E, Yurdakul B, Akşit F. Gebelerde rubella ve sitomegalovirus infeksiyonu. İnfeksiyon Derg (Turkish Journal of Infection) 1997:11; 325-7.
20. Aksit S, Egemen A, Ozacar T, Kurugol Z, Keskinoğlu P, Tasbakan M, Caglayan S.
Pediatr Infect Dis J 1999; 18(7): 577-80.

Thank you for copying data from http://www.arastirmax.com