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Çocuklukta Görülen Bir Konjonktival Yassı Epitel Hücreli Karsinom Olgusu

A Case of Conjunctival Squamous Cell Carsinoma Appeared in Childhood

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Abstract (2. Language): 
A case of conjunctival squamous cell carcinoma and the treatment methods are discussed with respect to a case with findings arising at an uncommon age and sex. An eleven years old girl applied to our out patient clinic with a mass on the lefte eye. Parents informed that the mass showed enlargement. There was a mass located on the temporal part of the left eye 3 mm lateral from limbus. The dimensions of the lesion was 3x3 mm and it was a vascularized, mobile, keratinizated and brown mass. Excision of the mass with a lateral margin of 3 mm, combined with couterization of the bases was performed. Mitomycin C was locally applied of 0.2 mg/ml for about two minutes use of sponge. The mass was reported as conjunctival squamous cell carsinoma after histopathological examination. Four months after the operation there was no evidence of recurrence. Conjunctival lesions should bring into mind to possibility of conjunctival squamous cell carsinoma even if it apprears at an uncommon age and sex, and should be treated with appropriate methods..
Abstract (Original Language): 
Bu çalışmanın amacı olağan olmayan bir yaş ve cinsiyette gözlenen konjonktival yassı epitel hücreli karsinom vakasını ve tedavi yöntemlerini değerlendirip, tartışmaktır. 11 yaşında bir kız çocuğu sol gözünde 5-6 yıldır geçmeyen bir kitle ile polikliniğimize getirildi. Hasta yakınları kitlede herhangi bir büyüme olmadığını, hep aynı büyüklük ve şekilde olduğunu ifade ettiler. Hastanın yapılan muayenesinde sol göz temporalinde limbustan 3 mm lateralde 3x3 mm boyutlarında hafif kabarık, vaskülarize, hareketli, keratinize ve kahverengi kitle mevcuttu. Operasyonda kitle, 3 mm'lik cerrahi sınır dahil edilerek çıkarıldı. Koterizasyon ve bölgeye bir sponç yardımı ile mitomisin C, 0,2 mg/ml 2 dakika süre ile uygulandı. Histopatolojik inceleme sonucu kitlenin konjonktival yassı epitel hücreli karsinom olduğu görüldü. Hasta aylık takibe alındı, 4 aylık takibinde nüks görülmedi. Konjonktival lezyonlarda, olağan dışı bir yaş grubu ve cins olsa dahi yassı hücreli karsinoma akla getirilerek uygun yöntemlerle tedavi edilmelidir.
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REFERENCES

References: 

1. Lee GA, Hirst LW. Ocular surface squamous neoplasia. Surv Opthalmol 1995; 39: 429-50.
2. Erie JC, Campbell RJ, Liesegang J. Conjunctival and corneal intraepithelial and invasive neoplasia. Opthalmology 1986; 93: 176-83.
3. Iliff WJ, Marback R, Gren WR invasive squamous cell carcinoma of the conjunctiva. Arch Opthalmol 1975; 93: 119-22.
4. Newton R, Ferlay J, Reeves G, Beral V, Parkin DM. Effect of ambient solar ultraviolet radiation on incidence of squamous-cell carcinoma of the eye. Lancet. 1996 May 25;347(9013):1450-1.
5. Margo CE, Mack W, Guffey JM. Squamous cell carsinoma of the conjunctiva and human immunodeficiency virus infection. Arch Opthalmophthalmol 1996; 114: 349.
6. Bunns DR, Tse DT, Folberg R. Microscopically controlled excision of conjunctival squamous cell carsinoma. Am J Opthalmol 1994; 117: 97-102.
7. Scott IU, Karp CL, Nuovo GJ. Human papillomavirus 16 and 18 expression in conjunctival intraepithelial neoplasia. Opthalmology 2002; 109: 542-7.
8. Lopez Garcia SF, Elosua De Juan I, Gonzales Morales ML, et al. Squamous cell carsinoma of the conjunctiva with orbital invasion. Arc Soc Esp Oftalmol 2000; 75(9): 637-41.
9. Akpek EK, Polcharoen W, Chan R, Foster CS. Ocular surface neoplasia masquerading ase chronic blepharoconjunctivitis. Cornea 1999; 18: 282-8.
10. Ersoz C, Yagmur M, Ersoz TR Yalaz M Preoperative brush and impression cytology in ocular surface squamous neoplasms. Acta Cytol 2003; 47(1): 13-5.
11. Grossniklaus HE, Stulting RD, Gansler T, Aaberg TM Jr. Aspiration cytology of
conjunctival surface. Acta Cytol 2003; 47(2): 239-46.
12. Nolan GR, Hirst LW, Wright RG, et al. Application of impression cytology to the diagnosis of conjunctival neoplasms. Diagn Cytopathol 1994; 11:246-9.
13. Schechter BA, Schrier A, Nagler RS, Smith EF, Valesquez GE. Regression of persumet primary conjunctival and corneal intraepithelial neoplasia with topical interferon a2b. Cornea 2002; 21: 6-11.
14. Panda A, Bajaj MS, Balasubramanya R, Parakash G. Topical mytomycin C for conjunctival-corneal squamous cell carsinoma. Am J Opthalmol 2003; 135(1). 122-3.
15. Mc Kelvie PA,Daniell M.impression cytology following mitomycin C therapy for ocular surface squamous neoplasia. Br J Opthalmol 2001; 85: 1115-9.

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