You are here

İzole Koroner Arter Ektazisinin Yaş Gruplarına Göre Dağılımı

Distribution of Isolated Coronary Artery Ectasy According to Age Groups

Journal Name:

Publication Year:

Abstract (2. Language): 
Objective: Coronary artery ectasy (CAE) is focal or diffuse dilation of coronary arteries. Age is a strong risk factor for coronary artery disease (CAD). We aimed to whether age is important for isolated CAE development and compare the patients with CAE and CAD in respect to age, sex and other cardiovascular risk factors. Methods: The study was carried out on 32 patients with isolated CAE and 100 patients with CAD. The patients were divided into 4 groups according to their age. The groups were classified as Group I:<50 years, Group II: 50-59 years, Group III: 60-69 years, Group IV: >70 years. Results: Mean ages of the patients with isolated CAE and CAD were 60.6±9.9 years and 61.4±9.5 years, respectively. There was no statistically significant difference between two groups in respect to age, sex and age distribution (p>0.05). Presence of hypertension, DM, smoking and other risk factors were also compared between two groups. DM and previous MI were more frequent in patients with CAD (p<0.05). The other risk factors were not different between CAD and CAE groups (p >0.05). Conclusions: We have shown that age is not a major determinant for isolated CAE development. Risk factors other than DM were found to be similar to patients with CAD.
Abstract (Original Language): 
Amaç: Koroner arter ektazisi (KAE) koroner arterlerin fokal ya da diffüz dilatasyonudur. Yaş koroner arter hastalığı (KAH) için güçlü bir risk faktörüdür. Biz yaşın izole KAE gelişiminde önemli olup olmadığını ve izole KAE olguları ile KAH olgularının yaş, cinsiyet ve diğer kardiyovasküler risk faktörleri yönünden karşılaştırılmasını amaçladık. Yöntemler: Çalışma izole koroner arter ektazili 32 hasta ve koroner arter hastalığı olan 100 hasta üzerinde yapıldı. Hastalar yaş gruplarına göre 4’ e bölündü. Gruplar, Grup I: < 50 yaş, Grup II: 50-59 yaş, Grup III: 60-69 yaş, Grup IV: > 70 olarak ayrıldı. Bulgular: İzole KAE’li hastaların ortalama yaşları 60.6±9.9, KAH grubunun ortalama yaşları 61.4±9.5 olarak bulundu. İki grup arasında yaş, cinsiyet ve yaş grupları açısından istatistiki anlamlı fark saptanmadı (p>0.05). Her iki grup hipertansiyon, sigara, diabet ve diğer risk faktörleri yönünden de kıyaslandı. DM ve MI öyküsü KAH’lı hasta grubunda daha yüksek bulundu (p<0.05). Diğer risk faktörleri KAE ve KAH gruplarında farklı değildi (p>0.05). Sonuç: Biz yaşın KAE gelişiminde ön planda olmadığını gösterdik. DM dışında diğer risk faktörlerinin koroner arter hastalığı bulunan hastalarla benzer olduğu bulundu.
203-207

REFERENCES

References: 

1. Hartnell GG, Parnell BM, Pridie RB. Coronary artery ectasia, its
prevalence and clinical significance in 4993 patients. Br Heart J
1985;54:392–5.
2. Markis JE, Joffe CD, Cohn PF, Feen DJ, Herman MV, Gorlin R.
Clinical significance of coronary artery ectasia. Am J Cardiol
1976;37:217–22.
3. Oliveros RA, Falsetti HL, Carroll RJ, Heinle RA, Ryan GF.
Arteriosclerotic coronary artery aneurysm. Report of five cases
and a review of the literature. Arch Intern Med 1974;134:1072–6.
4. Swaye PS, Fisher LD, Litwin P, Vignola PA, Judkins MP, Kemp
HG, et al. Aneurysmal coronary artery disease. Circulation
1983;67:134–8.
5. Sudhir K, Ports TA, Amidon TM, Goldberger JJ, Kane JP, Youc
P, Malley MJ. Increased prevalance of coronary ectasia in
heterozygous familial hypercholesterolemia. Circulation
1995;91:1375-80.
6. Hawkins JW, Vacek JL, Smith GS. Massive aneurysm of the left
main coronary artery. Am Heart J 1990;119:1406-8
7. Swanton RH, Lea Thomas M, Coltarte DJ, Jenkins BS, Webb-
Peploe MM, Williams BT. Coronary artery ectasia, a variant of
occlusive coronary arteriosclerosis. Br Heart J 1978; 40:393–400.
8. Befeler B, Aranda JM, Embi A, et al. Coronary artery aneurysm.
Study of their etiology, clinical course and effect on left
ventricular function and prognosis. Am J Med, 1977; 62:597-607.
9. Falsetti HL, Carroll RJ. Coronary artery aneurysm. Chest
1976;69:630–6.
10. Demopoulas VP, Olympios CD, Fakiolas CH, et al. The natural
history of aneurysmal coronary artery disease. Heart 1997;78:36-
151.
11. Genda A, Nakayama A, Shimizu M, Nunoda S, Sugihara N,
Suematzu T, Kita Y, Yoshimura A, Koizumi J, Mabuchi H, et al.
Coronary angiographic characteristics in Japanese patients with
heterozygous familial hypercholesterolemia. Atherosclerosis
1987; 66:29-36.
12. McGill HC Jr, McMahan CA, Malcom GT, et al. Effects of
serum lipoproteins and smoking on atherosclerosis in young men
and women. The PDAY Research Group: Pathobiological
Determinants of Atherosclerosis in Youth. Arterioscler Thromb
Vasc Biol 1997;1:95-106.
13. Berenson GS, Srinivasan SR, Bao W, et al. Association between
multiple cardiovascular risk factors and atherosclerosis in
children and youngs adults. The Bogalusa Heart Study. N Engl J
Med 1998;338:1650-6.
14. Melvin D. Cheitlin, Douglas P. Zipes. (Chapter 57)
Cardiovascular Disease in the Elderly. In: Braunwauld E, Zipes
D, Lippy P (eds ). Heart Disease. A Textbook of Cardiovascular
Medicine. 6. edition. 2001; 2019-38.
15. Williams MJA, Stewart RAH. Coronary artery ectasia, local
pathology or diffuse disease. Cathet Cardiovasc Diagnosis
1994;33:116-19.
Distribution of Isolated Coronary Artery Ectasy According to Age Groups
207
16. Sorrel VL, Davis MJ, Bove AA. Origins of coronary artery
ectasia. Lancet 1996;347:136-7.
17. Vaitkevicius PV, Fleg JL, Engel JH, et al. Effects of age and
aerobic capacity on arterial stiffnes in healt adults. Circulation
1993;88:1456-62.
18. Sonesson B, Lanna T, Vernersson E, Hansen F. Sex differences
in the mechanical properties of the abdominal aorta in human
beings. J Vasc Surg. 1994;20:959.
19. Stajduhar KC, Laird JR, Rogan KM, Wortham DC. Coronary
arterial ectasia: increased prevalance is patients with abdominal
aortic aneurysm as compared to occlusive atherosclerotic
peripheral vasculardisease. Am Heart J 1993;125:86-92.
20. Kishi K, Ito S, Hiasa Y. Risk factors and incidence of coronary
artery lesions in patients witha bdominal aortic aneurysm. Intern
Med 1997;36:384-8.
21. Bengtsson H, Bergquist D, Sternby NH.Increased prevalance of
abdominal aortic aneurysms. The changing natural history. J Vasc
Surg 1984;1:6.
22. Prisant LM. Abdominal aortic aneurysm. J Clin Hypertens
(Greenwich) 2004;6:85-9.
23. Nichols WV, O'Rourke MF. McDonald's blood flow in arteries,
in Arnold E. (ed): Theoretical, Experimental and Principles. 3 ed.
London, Melbourne, Auckland, 1990; pp:77–142, 216–269, 283–
269, 398–437.
24. Benetos S, LaurentAP, Hoeks P Boutouyrie and M. Safar,
Arterial alterations with aging and high blood pressure. A
noninvasive study of carotid and femoral arteries. Arterioscler
Thromb 1993;13:90–7.
25. Laurent S, Hayoz D, Trazzi S, Boutouyrie P, Waeber B, Omboni
S, Brunner HR, Mancia G, Safar MJ Isobaric compliance of the
radial artery is increased in patients with essential hypertension. J
Hypertens 1993;11:89–98.
26. Cox RH. Basis for the altered arterial wall mechanics in the
spontaneously hypertensive rat. Hypertension 1981;(3):485–95.

Thank you for copying data from http://www.arastirmax.com