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G Protein Aracılı Sinyal İletimi

G protein-mediated signal transduction

Journal Name:

  • İnönü Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 1995

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
In the last few decades, a lot of progress has been made in intemeuronal signal transmission and integration. There is an explosion of new information on neuropeptides, receptor subtypes, and G proteins. G proteins function as most important communication intermediaries in the cell. Stimulation of a G protein coupling receptor initiates a cascade of biochemical processes that produce both intra and intercellular signals. G proteins couple between cell surface receptors to a variety of enzymes and ion channels. In this review the role of G proteins of transmembrane signalling in central nervous system is emphasized.
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Abstract (Original Language): 
Son yıllarda sinir hücreleri arasında bilgi iletimi ve işlenmesi alanında önemli aşamalar kaydedilmektedir. Özellikle nöropeptidler, reseptör subtipleri ve G proteinleri hakkında yeni bilgilerde patlama gözlenmektedir. Bunlardan G proteinleri hücre içi iletişimde çok önemli aracılar olarak fonksiyon görürler. Bir reseptörün uyarılması, intrasellüler sinyal oluşturan biyokimyasal işlemler zincirini başlatır. G proteinleri birçok enzim ve iyon kanalıyla hücre yüzey reseptörleri arasında bağlantıyı sağlar. Bu derlemede santral sinir sistemindeki membran sinyal geçişinde G proteinlerinin rolüne dikkat çekilmiştir.
FULL TEXT (PDF): 
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  • 3
298-303
  • Turkish

REFERENCES

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