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Giardiazisli Çocuklarda Serum Çinko, Bakır ve Magnezyum Düzeyleri

Serum zinc , copper and magnesium levels in children with giardiasis

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Abstract (2. Language): 
Serum zinc, copper and magnesium levels were determined before and after antigiardia treatment in 30 children (between 2.5-13 years of age) with symptomatic giardiasis by atomic absorption spectrophotometry (AAS). Before the treatment, serum zinc, copper, and magnesium levels were 66.38±19.6 pg/dl, 96.4±24 pg/dl and 2.7±0.3 mg/dl, respectively. After the treatment (with metronidazole 20 mg/kg/day for 10 days), serum zinc, copper, and magnesium levels were 70.7±19.2 pg/dl, 84.2±16.4 pg/dl and 2.0±0.3 mg/dl, respectively. After the antigiardia treatment, serum copper concentrations were found significantly low (p<0.05). No significant differences were found in serum zinc and magnesium levels between before and after the treatment. [Journal of Turgut Özal Medical Center 1996;3(4):311-314]
Abstract (Original Language): 
Yaşları 2.5 ile 13 arasında değişen 21'i erkek, 9'u kız 30 semptomatik giardiazisli çocukta tedavi öncesi ve sonrasında serum çinko, bakır ve magnezyum seviyeleri ölçüldü. Tüm analizler "atomic absorption spectrophotometry" yöntemi ile gerçekleştirildi. Metronidazole tedavisi öncesinde ortalama serum çinko, bakır ve magnezyum seviyeleri sırasıyla 66.38 ± 19.6 pg/dl, 96.4± 24 pg/dl ve 2.7± 0.3 mg/dl olarak bulundu. Tedavi (metronidazole 20 mg/kg/gün 10 gün süre ile) sonrasındaki ortalama çinko, bakır ve magnezyum seviyeleri ise sırasıyla; 70.7±19.2 pg/dl, 84,2± 16.4 pg/dl, ve 2.0±0.3 mg/dl idi. Tedavi öncesi ve sonrası serum bakır seviyeleri arasındaki farklılık istatistiksel olarak anlamlıydı (p<0.05). Serum çinko ve magnezyum seviyeleri arasında ise anlamlı bir farklılık tesbit edilmedi (p>0.05). [Turgut Özal Tıp Merkezi Dergisi 1996;3(4):311-314]
311-314

REFERENCES

References: 

1. Prasad AS. Trace Elements in Human Health and Disease. Newyork Academic Press, 1976;14:228.
2. Gordon EF, Gordon RC, Passal DB. Zinc metabolism, basic clinical and behavioral aspect. J Pediatr 1981;90:34.
3. Zlothin SH, Buchanan BE. Meeting zinc and copper intake requirements in the paranterally fed preterm and full-term
infant. J Pediatr 1983;103: 441.
4. Mansar J.L Cromfard CS. Tyrok EE. et al. Serum copper concentrations in sick and malpreterm infant. J Pediatr 1980;97:753.
5. Tanoka Y, Hatona S, Nishi Y. Nutritional copper deficiency in a Japanese infant on formula. J Pediatr 1980; 96:255.
6. Ashkmazi A, Lenin Djaldetti M. The syndrome of neonatal copper deficiency. Pediatrics 1973; 52:525.
7. Von Collie, Bertrand M, Bieville FD, et al. Trace metals in cystic fibrosis. Acta Pediatr Scand 1982;71:203.
8. Both CC, Babovris N, Hanna S, Mac Intyre I. Incidence of hypomagnesemia in intestinal malabsorption. Br Med J
1963; 3:141.
9. Pickening LK; Engelkirk PG. Giardia lamblia. Pediatr Clin
N Am 1988; 35:565.
10. Sandsfead HH, Prasad AS, Sochvkrt AR, et al. Human zinc deficiency, endocrine manifestations and response to
treatment. Am J Clin Nutr 1967; 20:422.
11. Farthing MJG, Keusch GT, Coray MC. Effects of bile and
salts on growth and membrane lipid uptake by Giardia
lamblia. J Clin Invest 1985; 76:1727.
12. Tandon BN; Tandon RK, Salpathy BK, et al. Mechanism of malabsorption in giardiasis. A study of bacterial flora on bile salt deconjugation in upper jejunum. Gut 1977;18:
176.
13. Felman YM, Nikitas JA. Giardiasis. Cutis 1985;30:106.
14. Saha TK, Ghosh TK. Invasion of small intestinal mucosa by giardia lamblia in man. Gastroenterology 1977;72:402.
15. Hartong WWA, Gorky WK, Arvahitakis C. Giardiasis
clinical spectrum and functional structural abnormalities of the small intestinal mucosa. Gastroenterology 1979;77:61.
16. Moreky R, Parker JC. Ultrastructural studies of the human Giardia lamblia and subjacent jejunum mucosa in a subject with steatorrhea. Gastroenterolgy 1977;52:151.
17. Vizia BD, Poggi V, Vajro P et al. Iron malabsorption in
giardiasis J Pediatr 1985; 107: 75.
18. Rodriguez A, Soto G, Torres S, et al. Zinc and copper in hair and plasma of children with chronic diarhea. Acta Pediatr Scand 1985; 74: 770.
19. Naveh Y, Ligthman A, Zinder O. Effect of diarrhea on serum zinc concentrations in infants and children J Pediatr
1982;101:730.
20.
copper levels in giardiasis. In: Trace Elements in Health and Disease Yüregir GT, Donma O (eds) 3. International Congress of Trace elements in Health and Disease 1989;
Adana 31 March

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