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Skabies'te serum immünglobülin ve kompleman düzeyleri

Serum Immunoglobulin and Complement Levels in Scabies

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Abstract (2. Language): 
The human immune system interacts bidirectionally with environmental, metabolic, and endocrine factors as well as with infectious agents and is arranged genetically. Scabies is an important parasitic skin disease that continues to persist all over the world despite the availability of many acaricides and therapeutic tools. Individuals with scabies react to parasite mainly by generating a cell-mediated immune response. Immunologic reactions mediated by antibodies of the immunoglobulin G (IgG), IgM, and especially, IgE classes may also be involved. None of these reactions have been shown to eliminate all mites from the skin surface, but locally these reactions may prevent the epidemic multiplication of scabies' organisms on the skin surface, as observed in some patients with Norvegian scabies. The purpose of this study was to determine antibody response and changes in serum levels of some complement componenes in scabies. [Journal of Turgut Özal Medical Center 1997;4(1):37-39]
Abstract (Original Language): 
İmmün sistem; çevresel, metııbolik, endokrin ve enfeksiyöz faktörlerle karşılıklı etkileşim içinde olup bu ilişkiler genetik olarak düzenlenmektedir. Skabies, çeşitli ilaçlar ve tedavi yaklaşımlarına rağmen dünyanın her tarafında görülmeye devam eden önemli bir paraziter deri hastalığıdır. Skabies 'te immün cevap esas olarak hücresel immün sistem (geç tip hipersensitivite) tarafından oluşturulmaktadır. Bunun yanında skabies'e karşı antikor cevabı da oluşmaktadır. Bazen bütün parazitler temizlenemese de, immün reaksiyonlar etkenin kontrolsüz şekilde çoğalmasını önleyerek eliminasyonuna yardımcı olur. Bu çalışmanın amacı; skabieste gelişen antikor cevabını ve kompleman değişikliklerini araştırmaktır. [Turgut Özal Tıp Merkezi Dergisi 1997;4(1):37-39]
37-39

REFERENCES

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