You are here

Kronik Sigara İçicilerde Anestezi Sırasında ve Derlenme Odasındaki PO2 ve ETCO2 Değişiklikleri

PO2 and ETCO2 changes in chronic smokers during anaesthesia and in the recovery room

Journal Name:

Publication Year:

Abstract (2. Language): 
We compared the changes in ventilation parameters during anaesthesia and recovery room in chronic smokers and non smokers (15 chronic smokers and 15 non smokers). All patients were nomal clinically and paraclinically. The induction of anaesthesia was provided by 7 mg/kg Na thiopenthal and 0.8 mg/kg atracrium. Anaesthesia maintained 40% O2, 60% N2O and 1-1.5% isoflurane. ETCO2 (end tidal CO2) and SaO2 were measured for every 5 minutes during the operation. Hypoxia and avakening scores were measured in the recovery room. The only difference that observed between two group was SaO2 at the time of extubation and this result was statistically insignificant. A 13% decrease in ETCO2 was observed in chronic smokers. Chronic smokers avakened later than non smokers, and their secretions were also more than non smokers. Non smokers did not cough at the recovery room but chronic smokes coughed at a percentage of 20%. Morbidity was 41% in the chronic smokers group. We concluded that smoking must be avoided for the chronic smokers at least a few days before operation. [Journal of Turgut Özal Medical Center 1997;4(4):413-417]
Abstract (Original Language): 
Günümüzde sigara içici sayısının çok fazla olması nedeniyle çalışmamızda sigara içmeyen ve içen sağlıklı yetişkinlerde anestezi esnasında ve derlenme odasında solunum parametreler indeki değişiklikleri inceleyip karşılaştırdık. Çalışmaya sigara içen 15, içmeyen 15 olmak üzere 30 hasta alındı. Bütün vakaların gerek klinik, gerek laboratuar bulguları tamamen normaldi. Bütün vakalara 7 mg/kg tiyopental ve 0.8 mg/kg atraküryum verilerek indüksiyon sağlandı. İdame anesteziye % 40 02 ,% 60 N2O ve % 1-1,5 Isofluranla devam edildi. Operasyon esnasında her 5 dakikada ETC02 (end tidal CO2), SaO2 (oksijen satürasyonu), ölçülüp kaydedildi. Derlenme odasında hipoksi ve uyanma skorları ölçülüp kaydedildi. Sa02 da iki grup arasında sadece ekstübasyon sırasında farklılık gözlendi. Bu fark istatistiksel olarak anlamsız (p>0.05) idi. Sigara içen grupta ETCO2 daha geç uyandığı ve sekresyon artışının daha fazla olduğu tespit edildi. Sigara içmeyen grupta derlenme odasında öksürük gözlenmezken, içen grupta % 20 oranında öksürük gözlendi. Sigara içen grupta derlenme odasındaki toplam morbidite % 41 idi. Sonuç olarak operasyona alınacak hastalar sigara içiyorlarsa operasyondan bir kaç gün önce bir aktır ılmasının uygun olacağı kanısına vardık [Turgut Özal Tıp Merkezi Dergisi 1997;4(4):413-417]
413-417

REFERENCES

References: 

1. Bassenge E, Holtz J, Strohschein H. Sympatoadrenal activity and sympathoinhibitory hormones during acut and cronic nicotine application in dogs. Klin Wochenschr 1988: 11-2.
2. Bigler, et al. Gastric pH and volume in smoker and nonsmoker patients. ACTA Anestesiol 1990:30-5.
3. Merfluttz FD, Brand L, Nick D. The use of pulse oximetry in dedecting disorders of the arterial oxygen status in the immediate postoperative phase exemplified by combination anaesthesia with isoflurane. Anaest Intensivther Nottfallmed 1989;24(1):27.
4. Hudes ET, et al. Recovery room oxigenation:a comparision of nasal catheters and %40 oxygen mask. Can J of Anaesthesia 1989;36(1):20.
5. Dueck R, Prutow RJ, Davies DJ, et al. The lung volume at which shunting occur with inhalation anaesthesia.
Anaesthesiology 1988;69(6):854.
6. Deller A, Stenz R, Forstner K, Schreiber MN, Konrat F, Fosel. Carbomonoxyhemoglo-bin and methemoglobin in patients with and without a smoking history during ambulatory anaesthesia. Anaesthesia 1991;26(4):186.
7. Egan TD, Wong KC. Preoperative smoking cessation and anesthesia:a reviev. J Clin Anest 1992; 4(1):63.
8. Rao MK, et al. Analysis of risk factors for postoperative pulmonary complications in head and neck surgery.
Laryngoscope 1992;102(1):45.
9. Beckers S, Camu F. The anesthetic risk of tobacco smoking.
ACTA Ane 1992:42-5.
10. Fletcher R. Dead space in anaesthesia ACTA anasthesiol
Scann suppl 1990;94:46.
11. Taid AR, Kyff TV, Crider B, et al. Changes in arterial O2 saturation in cigarette smokers following general anaesthesia.
Can J Anaesthesia 1990;37(4 pt 1):423.
12. Berkan T, et al. The effects of single use treatment with cigarette smoke on the blood levels and hemodynamic effects
of propronalol in rats. Eur J Drug Met Ph 1989;14:221.
13. Guidotti TL, Laing L, Prakash UB. Clove cigarettes.The basis for concern regarding healt effects.West J Med 1989;151:220.
14. Husum B, Valentin M, Wulf HC, Halaburt A, Niebuhr E.
Sister chromatit exchanges in cigarette smokers : Effects of halotane isofluran or subarachnoid blockage. Br J Anaest
1985; 57:1100.
15. Jackson CV. Preop.Pulmoner evaluations. Arch Int Med 1988;
148(10):2120.
16. Prien T, Traber LD, Herndon DN, Stothert JC, et al. Pulmonary edema with smoke inhalation,undedected by indicator dilition
tecnique. J Apply Physiol 1987;63:907.
17. Diamond L, Kimmel EC, Lai YL, Winsell DW. Eugmentation of elastase-induced emphysema by cigarette smoke.Effects of reduced nicotine content. Am Rev Respir Disease
1988;138(5):1201.
18. Jones RJ, Rosen M, Saymour L. Smoking and anaesthesia
1987;42:1.
19. Hammond EC, et al. Smoking and deat rates part 1 JAMA 166-1159 part 2 JAMA 1984;251:2854.
20. Doll R. Smoking and deat rates JAMA 1984;251:2854.
21. Ross AJ, Tinker JH. Anaesthesia 3. edition Vol 1 Chapter 22
715-742
22. Wright DJ, et al. Smoking and gastric juice volum
Can.An.S.J.26-328-1974
416
Turgut Özal Tıp Merkezi Dergisi 4(4): 1997
et al.
PO2 and ETCO2 changes in chronic smokers
23. Adelhoj et al. Influence of cigarette smoking on the risk of acit pulmonary aspiration ACTA Anesthesiol Scand. 1974;31:7.
24. Spielberger CD, et al. Personality andsmoking behavior. J Pers
Asses 1982;46:396.
25. Hoeppner VH, et al. Relationship between elastic recal and closing volume in smokers and nonsmokers
26. Le Blanch P, Ruft F, Milic-Emili J. Effects of age and body position on airway closure in man. J Appl Physiol
1970;28:488.
27. Mansell A, et al. Airway closure in children. J Appl Phisiol
1972;33:711.
28. Warmer MA, et al. Role of preoperative cessation of smoking and other factors in postoperative pulmonary complications:a blindan prospective study of coroner arter by-pass patients.
Mayo Clin Proc 1989; 64:609.
29. Robinson K, et al. When does the risk of acutecoronary heard disease in ex-smokers fall to that in nonsmokers.A retrospective study of patient admitted to hospital with a first episode of miyocardial in fonction or unstable. AP Br Heard J
1984;62:16.
30. Rosenberg L, et al. The risk of MI after quitting smoking in man under 55 years age. N Eng J of Med 1985; 313:1511.
31. Gordon J, et al. Death and coronary attacks in man after giving up smoking. Lancet 1974;2:1345.
32. Jajitch et al. Smoking and CAD mortality in the elderly. JAMA
1984;252:2831.
33. Ernest et al. Abstention from chronic cigarette smoking normalizes blood rheology. Atherosclerozis 1987;64:75.
34. Galae G, et al. Haematological and haemrheological changes assosiated with cigarette smoking. J Clin Pathol 1985;38:978.
35. Wormer et al. Preoperative cessation at smoking and pulmonary complications in pulmonary dysfonction.
Anaesthesiology 1984;61:579.
36. Pearce AC, Jones RM. Smoking and anaesthesia. Preoperative abstinence and perioperative morbidity. Anaesthesiology
1984;61:579.
37. Jones RM. Smoking before surgery. The case of stopping
smoking. Br Med J 1985;290:1763.
38. Devies JM, et al. Effects of stopping smoking for 48 hours on oxigen availability from the blood.A study on pregnand
woman. Br Medical J 1979; 2:355.
39. Haas A, et al. Therapeutic modalities P.110 in pulmonary therapy and rehabilitation: Principles and practice 1st edition Williams and Wilkins Baltimore 1984.
40. Veith FJ, Rocco AG. Evaluation of respiratory function in surgical patients importance at preoperative preparation and the prediction of pulmonary complications. Surgery
1959;45:905.
41. Sabavata PB, et al. Surgery of the aorta its branches
Anaesthesiology 1970;33:229.
42. Diehl JT, Cali RF, Hertzer NR. Complications of abdomnal aortic reconstruction ana-lyzis of perioperative risk factors in
557 patiants. Ann Surgery 1983;49:197.
43. Young AE, Sandberg GW, Couch NP. The reduction of mortality of abdominal aortic anevrysm resection. Am J Surg
1977;134:585.
44. Tisi GM. Preoperative evaluation of pulmonary function.Validity,indications and benefits. Am Rev Respir
Disease 1979;119:293.
45. Pearce AC, Jones RM. Smoking and anaesthesia:Preoperative abstinence and preoperative morbidity. Anaesthesiology
1984;61:576.
46. Tarhan S, Moffitt EA, Sessler AD, et al. Risk of anaesthesia and surgery in patients with chronic bronchitis and chronic pulmonary disease. Surgery 1973;74:720.
47. Stein M, Cassara EL. Preoperative pulmonary evaluations and
therapy for surgery patients. JAMA 1970;211:787.

Thank you for copying data from http://www.arastirmax.com