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Serum immünoglobulin ve atopik dermatit HASTALARDA TAMAML DÜZEYLERİ

SERUM IMMUNOGLOBULINS AND COMPLEMENT LEVELS IN PATIENTS WITH ATOPIC DERMATITIS

Journal Name:

  • İnönü Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 1998

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
In this study, to research the pathological role of immunological changes in atopic dermatitis, we investigated the serum immunoglobulins and complement levels and the correlations between severity scoring of atopic dermatitis (scorad index) and these parameters. There was no statistically significant difference in the serum IgA, IgM, IgE, and C4 levels between the patients with atopic dermatitis and controls. But, the serum C3 and IgG levels was significantly lower in the patients than in controls There was no correlation between scorad index and the serum IgG, IgM, and IgElevels, but the negative correlation between scorad index and the serum IgA and C3 levels and positive correlation between scorad index and the serum C4 levels This findings suggest that immunoglobulins and complement system participates in inflammatory process in atopic dermatition.
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Abstract (Original Language): 
Bu çalışmada, atopik dermatitde immünolojik faktörlerin patolojik rolünün araştırmak için, serum immünoglobulin ve kompleman seviyeleri ve bu parametrelerin atopik dermatitin şiddet skoru (scorad indeksi) arasındaki korelasyonlar araştırıldı. Atopik dermatitli hastalar ile kontroller arasında serum IgA, IgM, IgE ve C4 seviyeleri açısından fark bulunmadı. Fakat C3 ve IgG seviyeleri hastalarda düşük idi. Scorad indeksi ile serum IgG, IgM, IgE sev yeler arasında korelasyon yoktu, fakat scorad ndeks le IgA ve C3 sev yeler arasında negat f korelasyonlar ve scorad ndeks le serum C4 seviyesi arasında pozitif korelasyon bulundu. Bu bulgular gösterirki immünoglobulinler ve kompleman sistemi atopik dermatitdeki inflamatuar prosesteyeralmaktadır
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  • 2-3
162-164
  • Turkish

REFERENCES

References: 

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