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KAN VE KAN ÜRÜNLERİ TRANSFÜZYONU YAPILAN VE YAPILMAYAN HEMATOLOJİK MALİGNİTELİ HASTALARDA HEPATİT B VE HEPATİT C VİRÜS SEROPOZİTİFLİĞİ

Seropositivity of hepatitis B and hepatitis C viruses in blood and blood products in transfused and non-transfused patients with hematological malignancies

Journal Name:

  • İnönü Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 2000

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Objective: We investigated the seropositivity difference of hepatitis B and hepatitis C viruses in hematological^ malignant patients with history of blood and blood products transfusions. Material and methods: HBs Ag, Anti-HBs and anti-HCV antibody positivity were investigated in 35 hematologically malignant patients with history of transfusions and 52 patients without history of transfusions with EUSA in the department of Hematology. Results: Anti-HCV positivity was detected in 2.8% (n= 1) and 1.9% of patients (n= 1) with and without blood transfusion history, respectively. HBs Ag positivity was detected to be 22.8% (n= 8) in blood transfused group, and 5.7% (n= 3) in non-transfused group and 9% (n= 9) in the control group. Anti-HBs antibody positivity was detected in 31.4% of patients (n= 11) with a history of blood transfusion, 38.4% in the non-transfused group (n= 20), and 40% in the control group (n= 43). Conclusions: HBs Ag positivity was found to be significantly higher in the transfused group when compared with the non-transfused group and the control group (p<0.05).
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Abstract (Original Language): 
Amaç: Kan ve kan ürünleri transfüzyonu öyküsü olan ve olmayan hematolojik maligniteli hastalarda, hepatitB ve hepatit C virüs seropozitifliği arasındaki fark araştırıldı. Materyal ve metot: Hematoloji servisinde tedavi edilen, kan transfüzyon öyküsü olan 35 ve transfüzyon öyküsü olmayan 52 hematolojik maligniteli hastada HBs Ag, anti-HBs ve anti-HCV antikor pozitifliği EUSA yöntemi ile araştinldı. Bulgular: Çalışmamızda hematolojik malign hasisliği olup transfüzyon yapılmış ve transfüzyon öyküsü olmayan gruplarda birer hastada anti-HCV seropozitifliği saptandı (%2.8, %1.9). HBs Ag seropozitifliği transfüzyon yapılan hasta grubunda %22.8 (n=8), transfüzyon yapılmayan hasta grubunda %5.7 (n=3), kontrol grubunda ise %9 (n=9) olarak bulunmuştur. Anti-HBs antikor seropozitifliği transfüzyon yapılan hasta grubunda %31.4 (n=ll), transfüzyon yapılmayan hasta grubunda %38.4 (n=20), kontrol grubunda %40 (n=43) oranında saptanmıştır. Sonuç: Kan transfüzyonu yapılmış olan hematolojik maligniteli hastalarda HBs Ag seropozitifliği, kan transfüzyonu yapılmamış hasta ve kontrol grubundan daha yüksek bulundu (p<0.05).
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  • 2
109-112
  • Turkish

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Dinçe
r M, Aslan V, Gülbaş Z. Hematolojik hastalıklarda HBs Ag ve anti HCV pozitiflik oranlarının değerlendirilmesi. 27. Ulusal Hematoloji Kongresi Özet Kitabı, 153.

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