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MEME KARSİNOMLU OLGULARDA GÖRÜLEN İKİNCİ PRİMER KARSİNOMLAR: ALTI OLGU SUNUMU

Second Primary Tumors In Patients With Breast Carcinoma: Report Of Six Cases

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Abstract (2. Language): 
In the cancer therapy, the patient's survival and life quality have been increased with the use of chemotherapy and radiotherapy in addition to surgical therapy in the last years. On the other hand, because of either increased patient's survival or side effect oi adjuvant therapy, the risk of the development of second primary tumors have been increased. Although the risk of this condition is to be pretty low, the second primary tumors after the other primary tumors have been reported including the breast carcinoma. In addition, genetic factors may be playing a role in development of the tumor. In this study, six cases of breast carcinoma with second primary carcinoma, among of1073 breast carcinoma, that diagnosed at our department are presented. This second primary tumors were colon carcinoma in two cases, nasopharnyx carcinoma in one case, thyroid carcinoma in one case, endometrium carcinoma in one case ano cervical in situ carcinoma in one case. In this study, six cases of second primary tumor with breast carcinoma which were found to be interesting because of its rarity were presented.
Abstract (Original Language): 
Son yıllarda kanser tedavisinde cerrahi yöntemlere ek olarak kemoterapi ve radyoterapi gibi tedavi yöntemlerinin de yaygın olarak kullanılmasıyla, hastaların sağkalım süreleri ve yaşam kaliteleri artmıştır. Ancak hastaların hem yaşam sürelerinin artması, hem de bu adjuvan tedavilerin yan etkileri nedeniyle ikinci bir mal ignite gelişme riski de artmaktadır. Böyle bir risk faktörü oldukça düşük olmakla birlikte bir primer neoplazinin ardından gelişen ikinci mallgniteler bildirilmektedir. Meme karsinomları da bildirilen olgular arasında yer almaktadır. Ayrıca ikinci bir mallgnansinin gelişiminde genetik faktörler de rol oynayabilmektedir. Burada Dokuz Eylül Üniversitesi Tıp Fakültesi Patoloji AnablHm Dalı'nda tanı almış 1073 meme karsinomunun altısında gelişen ikinci prlmeı tümörler sunulmaktadır. Bu olgular meme karsinomu yanında ikinci primer olarak gözlenen iki kolon karsinomu, bir nazofarinks karsinomu, bir tiroid karsinomu, bir endometrium karsinomu ve bir serviks insltu karsinomudur. Bu tür olguların seyrek görülmesi nedeniyle ilginç bulunarak burada sunulmuştur.
351-354

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