You are here

Home » Content

Yatan Hastalardan îzole Edilen Gram Negatif Basillerde Antibiyotik Direnci

Antimicrobial Resistance of Gram Negative Bacilli Isolated From Inpatients

Journal Name:

  • İnönü Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 2001

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Due to overuse of antibiotics in hospitals, there has been increased bacterial resistance to antibiotics. This study was performed to establish the degree of antimicrobial resistance to various broa d spectrum agents used to treat infections caused by Gram negative bacilli. During a four month period, the sensitivities to antibiotics of 152 Gram negative bacilli collected from inpatients were detected by disk diffusion method. Among all microorganisms tested, the percentages of resistant strains were 53 for GN, 27 for AK, 23 for ISP, 58 for CTX, 59 for CRO, 34 for CAZ, 27 for CEF, 3 for IMP, 3 for MEM, 39 for PTZ, 56 for AMC, 46 for TIM and 54 for SAM.
Bookmark/Search this post with
Abstract (Original Language): 
Hastanelerde antibiyotiklerin aşırı kullanılmasına bağlı olarak bakteriyel direnç artmaktadır. Bu çalışma, Gram negatif basillerin neden olduğu infeksiyonların tedavisinde kullanılan geniş spektrumlu ajanlara karşı gelişen antimikrobiyal direnci saptamak amacıyla yapıldı. Dört aylık sürede yatan hastalardan izole edilen 152 Gram negatif basilin antibiyotiklere duyarlılıkları disk difüzyon yöntemi ile belirlendi. Test edilen 152 Gram negatif basilin antibiyotiklere direnç oranları GN için % 53, AK için % 27, ISP i çin % 23, CTX için % 58, CRO için % 59, CAZ için % 34, CEF için % 27, IMP için % 3, MEM için % 3, PTZ için % 39, AMC % 56, TIM için % 46 ve SAM için % 54 olarak bulundu.
FULL TEXT (PDF): 
PDF icon arastirmax-yatan-hastalardan-izole-edilen-gram-negatif-basillerde-antibiyotik-direnci.pdf
  • 4
193-196
  • Turkish

REFERENCES

References: 

1. Archibald L, Phillips L, Monne t D, et al. Antimicrobial resistance in isolates from inpatients and outpatients in the United States: Increasing importance of the intensive care unit. Clin Infect Dis 1997; 24: 211 -5.
2. National Committee for Clinical Laboratory Standards. Performance Stan dards for Antimicrobial Susceptibility Testing: Eighth Informational Supplement M2 -A7 Disk Diffusion. 1998; 14-21.
3.
Gü
r D. İsepamisin: Mikrobiyolojik özellikler. Hastane İnfek Derg 2001; 5: Ek 1: 3 -
7.
4. Sirot J. Detection of extended spectrum plasmid mediated beta lactamases by disk diffusion. Clin Microbiol infect 1996; 2: 35 -8.
5. Hughes JM, Tenover FC. Approaches to limiting emergence of antimicrobial resistance in bacteria in human populations. Clin Infect Dis 1997; 24 (Suppl 1):131-5.
6. Hancock REW. The role of fundamental research and biotechnology in finding solutions to the global problem of antibiotic resistance. Clin Infect Dis 1997; 24 (Suppl 1):148-50.
7. Acar JF. Consequences of bacterial resistance to antibiotics in medical practice. Clin Infect Dis 1997; 24 (Suppl 1):17-8.
8. Verbist L. Incidence of multi -resistance in Gram negative bacterial ısolates from ıntensive care units in Belgium a surveillance study. Scand J Infect Dis 1991; Suppl
78: 45-53.
9. Gerding DN. Antimicrobial cycling: Lessons learned from the aminoglycoside experience. Infect Control Hosp Eidemiol 2000; 21: 12 -7.
10. Çağatay A, Pınar M, Öncü S, et al. Aminoglycoside susceptibilities of Gram negative bacteria in intensive care units (abstract). Clin Microbiol and Infect 2001;7 (suppl 1): 72.
11.
Yüceso
y M, Biberoğlu K, Yuluğ N. İnfeksiyon etkeni Gram negatif bakterilerin antibiyotik duyarlılık paternlerinin E testi ile karşılaştırılması. İnfeks Derg 1996; 10:
229-33.
12.
Sönme
z E, Durmaz B, Özbilge H, Şahin K Gram negatif enterik bakterilerin antibiyotiklere in vitro duyarlılıkları. Yeni Tıp Derg 1996; 13: 164 -5.
13. Patterson JE, Hardin TC, Kelly CA, et al. Association of antibiotic utilization measures and control of multiple drug resistance in Klebsiella pneumoniae. Infect
Control Hosp Epidemiol 2000; 21 : 455-8.
14. Tekerekoğlu MS, Ayan M, Otlu B, et al. Klebsiella Sneumoniae suşlarında genişlemiş spektrumlu beta laktamazların ve antibiyotik duyarlılıklarının saptanması. Mikrobiyol Bült 2001; 35: 225-30.
15. Pfaller MA, Korten V, Jones RN, Doern GV. Multicenter evaluation of the antimicrobial activity for seven broad spectrum beta lactams in Turkey using the E
test method. Diagn Microbiol Infect Dis 1999; 35: 65 -73.
16. Aksaray S, Dokuzoğuz B, Güvener E. et. al. Surveillance of antimicrobial resistance among Gram neg ative isolates from intensive care units in eight hospitals in Turkey. J Antimicrob Chemother 2000; 45: 695 -9.
17. Sönmez E, Köroğlu M, Çınar Y, Durmaz B. Sefepim ve bazı üçüncü kuşak sefalosporinlerin Gram negatif bakterilere etkinliği. Ankem Derg 1998; 12: 45-9.
18. Garau J, Wilson W, Wood M, Carlet J. Fourth generation cephalosporins: a review of in vitro activity, pharmacokinetics, pharmacodynamics, and clinical utility. Clin
Micro Infect 1997; 3 (suppl 1): 87-101.
19. Karchmer AW. Cephalosporins. In: Mandell GL, Bennett JE, Dolin R, ed(s). Principles and Practice of Infectious Diseases. 5th ed. Philadelphia: Churchill
Livingstone 2000: 287.
20. Chambers HF. Other [3 lactam antibiotics. In: Mandell GL, Bennett JE, Dolin R, ed(s). Principles and Practice of Infectious Di seases. 5th ed. Philadelphia:
Churchill Livingstone 2000: 295.
21. Günseren F, Mamıkoğlu L, Öztürk S. et. al. A surveillance study of antimicrobial resistance of Gram negative bacteria isolated from intensive care units in eight hospitals in Turkey. J Antimic rob Chemother 1999; 43: 373 -8.
22. Kaye KS, Fraimow HS, Abrutyn E. Pathogens resistant to antimicrobial agents.
Infect Dis Clin North Am 2000; 14: 293 -313.
23. Hanberger H, Rodriguez JAG, Gobernado M. et. al. Antibiotic susceptibility among aerobic Gram negative b acilli in intensive care units in 5 European countries. Jama 1999; 281: 67 -71.
24. Yücesoy M, Yuluğ N, Ünal S. et. al. Antimicrobial resistance of Gram negative isolates from intensive care units in Turkey: comparison to previous three years. J
Chemother 2000; 12: 294-8

Thank you for copying data from http://www.arastirmax.com