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Study of sources of Coagulase Negative Staphylococci infection from NICU environment

Study of sources of Coagulase Negative Staphylococci infection from NICU environment

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Abstract (2. Language): 
Introduction: In recent years Coagulase negative staphylococci infections has emerged as a pathogen in growing number of serious nosocomial infections1. The shift in NICU bed utilization toward occupancy by babies who have the highest overall risk of developing nosocomial bloodstream infections is seen.With this consideration in mind the present study was planned to study different sources of Coagulase Negative Staphylococci infection from NICU environment. Materials & Methods: The present study was conducted in neonatal intensive care unit (NICU) of a tertiary care hospital over a period of one year. A Total of 972 neonates both preterm and fullterm, who were clinically suspected of having sepsis were included in the study. Blood, Pus, CSF and Urine specimen were collected. These samples were processed by standard bacteriological techniques. 269 samples from NICU environment were also collected during same time and period. Observations & Results: In our study shows that, majority of 100 CoNS were isolated from blood 58, followed by exudates 28 [Umbilical swab 9, Skin infection 10, Catheter tip 8, Conjunctival swab 1], CSF12 and urine 02. There was seen correlation between onset of septicemia with early onset < 48 hrs case were 36 while with late onset >48 hrs were 64 cases out of 100. Conclusion: There are few studies showing CoNS isolation rate more than the present study. This may consider as an interim study & hence more studies should occur in India & with more appropriate statistical analysis.
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REFERENCES

References: 

1. Sewell CM, Larridge JE, Young EJ, Guthrie RK. Clinical significance of coagulase
negative staphylococci. J Clin Microbiol 1982; 16: 236-239.
2. Kloos W.E., Bannerman T.L. Update on clinical significance of coagulase-negative
staphylococci. Clin Microbiol Rev1994 ; 7(1): 117-140.
3. Jain A, Agarwal J, Bansal S. Prevalence of Methicillin-resistant, coagulase negative
Staphylococci in neonatal intensive care units: Findings from a tertiary care hospital in
India. J Med Microbiol 2004 ; 53:941-944.
4. Sidebottom D.G., Freeman J., Platt R., Epstein M.F., Goldmann D.A. Fifteen-year
experience with blood stream isolates of coagulase negative staphylococci in neonatal
intensive care. J Clin Microbiol 1988;26(4): 713-718.
5. Kumar M, Agarwal SK, Roy I, Jain A. Bacteriology of neonatal septicaemia in a tertiary
care hospital of northern India. Indian J Med Microbiol 2002; 20(3): 156-159.
6. Koneman EW. Allen SD, Janda WM, Schreckenberger PC, Winn WC. The Gram
positive cocci, Part I: Staphylococci and related organisms. In: Color Atlas and Textbook
of Diagnostic Microbiology 6th edition (Lippincott) 2007:623-625.
7. Koneman EW. Allen SD, Janda WM, Schreckenberger PC, Winn WC. The Gram
positive cocci, Part I: Staphylococci and related organisms. In: Color Atlas and Textbook
of Diagnostic Microbiology 6th edition (Lippincott) 2007:623-624.
8. Roy I, Jain A Kumar M, Agarwal S.K. Bacteriology of neonatal septicemia in a tertiary
care hospital of northern India. Indian J of Medical Microbiol 2002; 20 (3): 156-159.
9. Aftab R, Iqbal I. Bacteriological agents of neonatal sepsis in NICU at Nishtar Hospital,
Multan. JCPSP 2006; 16(3):216-219
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10. Isaacs D, Barfield C, Clothier T, Darlow B, Ehrlich J, Grimwood K et al. Late onset
infections of infants in neonatal units. J American Peds 2006;117 (2):340-348.
11. Isaacs D, Barfield C, Clothier T, Darlow B, Ehrlich J, Grimwood K et al. Late onset
infections of infants in neonatal units. J American Peds 2006;117 (2):340-348.
12. Villari P, Sarnataro C, Iacuzio L. Molecular epidemiology of Staphylococcus epidermidis
in a Neonatal Intensive Care Unit over a three year period. J Clin Microbiol 2000; 38 (5):
1740-1746.
13. Lee C, Chen S., Tang Ren Bin, Hwang B.T. Neonatal bacteremia in a neonatal intensive
care unit: Analysis of causative organisms and antimicrobial susceptibility 2004; 67: 15-
20.
14. Barbara J.S., Hansen N., Fanaroff A.A. Late onset sepsis in very low birth weight
neonates: The experiences of the NICHD Neonatal Research Network Pediatrics
2002;110 (2): 285-291.

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