You are here

Home » Content

SCREENING FOR PHYTOCHEMICAL, ANTIBACTERIAL AND CYTOTOXIC ACTIVITY OF MEDICINAL PLANT OF TAMILNADU

Journal Name:

  • The International Journal of Pharmaceutical Research and Bio-Science

Publication Year:

  • 2012

Key Words:

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
The present study was designed to evaluate the phytochemical, antibacterial activity, cytotoxic activity and GC-MS analysis of the medicinal plant, Centella asiática. Methanol extract of this plant showed major phytochemicals and also showed good zone of inhibition for Pseudomonas sp. compare to other bacterial strains. The 47.6 ^g/ml of plant extract showed more cytotoxicity activity for A431 cell line. Nine compounds also identified in the GC-MS analysis of this plant. All the results conclusively validate that phytochemicals treasures indulged in centella asiatica plant.
Bookmark/Search this post with
FULL TEXT (PDF): 
PDF icon arastirmax-screening-phytochemical-antibacterial-and-cytotoxic-activity-medicinal-plant-tamilnadu.pdf
  • 1
  • English

REFERENCES

References: 

1. Chengjian Z and Luping Q: Chemical components of Centella asiatica and their bioactivities. Journal o f Chinese Integrative Medicine 2007; 5(3): 348-351.
2. Joy PP, Thomas J, Mathew S and Skaria
BP: Medicinal Plants. Tropical Horticulture (eds. Bose, TK, Kabir J, Das P. and Joy, PP.) Naya Prokash, Calcutta 2001; 2: 449¬632.
3. College G and Naka K: Antimicrobial and Antifungal Activity of Centella asiatica (L) Urban Umbeliferae. Journal of Ethno
pharmacology 2009; 2(2): 328-330.
4. Dash BK, Faruquee HM, Biswas SK, Alam MK, Sisir SM and Prodhan UK: Antibacterial and Antifungal Activities of Several Extracts of Centella asiatica L. against Some Human Pathogenic Microbes.
Life Sciences 2011: 1-5.
5. Panthi MP and Chaudhary RP: Antibacterial activity of some selected folklore medicinal plants from West Nepal. Scientific World 2006; 4(4): 16-21.
6. Ullah MO: Antimicrobial, Cytotoxic and Antioxidant Activity of Centella asiatica.
European Journal of Scientific Research 2009; 30(2): 260-264.
7.
Cohe
n ML: Epidemiology of drug resistance: implications for a post antimicrobial era. Science 1992; 257: 1050¬1055.
8.
Gislen
e GF, Juliana L, Paulo C, Freitas and Giuliana LS: Antibacterial activity of plant extracts and phytochemicals on antibiotic resistant bacteria. Brazilian Journal of Microbiology 2000; 31: 247-256.
9.
Ello
f JN: Which extract ant should be used for the screening and isolation of antimicrobial components from plants. Journal of Ethnopharmacol 1998; 60: 1-6.
10.
Harborn
e JB: Phytochemical methods, London. Chapman and Hall, Ltd. 1973: 49¬188.
11.
Treas
e GE and Evans WC: Pharmacology, Saunders Publishers,
London, 15th Edition (2002): 42-44, 221¬229, 246-249, 303-306, 331-332, 391-393.12. Mace ME: Histochemical localization of phenols in healthy and diseased tomato
roots, Phytopathology 1963; 16: 915-925.
13. Kokate CK: Practical Pharmacognosy, Vallabh Prakashan, New Delhi, 4th Edition (1994): 107.
14. Bauer RW, Kirby MDK, Sherris JC and
Turck M: Antibiotic susceptibility testing by single standard disc diffusion method, American Journal of Clinical Pathology
1966; 45: 493-496.

Thank you for copying data from http://www.arastirmax.com