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PHYTOCHEMICAL AND ANTI-ULCER ACTIVITY OF PETROLEUM ETHER AND CHLOROFORM EXTRACTS OF LEAVES OF ALANGIUM SALVIFOLIUM LINN. (FAMILY-ALANGIACEAE)

Journal Name:

  • The International Journal of Pharmaceutical Research and Bio-Science

Publication Year:

  • 2012

Key Words:

Author NameUniversity of Author
Abstract (2. Language): 
Alangium salvifolium Linn. (family-Alangiaceae), is found in different parts of India. It is widely used indigenously for different purposes. The present study is an attempt foe preliminary investi gation of phytochmical constituents and to explore the anti-ulcer activity of petroleum ether and chloroform extracts of leaves of Alangium salvifolium by developing gastric ulcer by pyloric ligation and aspirin + pyloric ligation model. The extracts were administered to experimental animals orally at the doses of 100mg and 200mg per kg with ulcer developed animals. Ranitidine (5mg/kg) was administered as standard drug. All the test doses were administered orally by making suspension with 0.5% carboxy methyl cellulose. The result is that the extracts have protective activity over ulceration because the parameters which were observed, total gastric volume, total acidity, free acidity, ulcer score index and gastric pH. The author compared the result at the standard
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