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BACTERIOLOGY OF PLEURAL FLUID INFECTIONS AT A TERTIARY CARE HOSPITAL

Journal Name:

  • The International Journal of Pharmaceutical Research and Bio-Science

Publication Year:

  • 2012

Key Words:

Author NameFaculty of Author
Abstract (2. Language): 
Bacterial infections are one of the most common causes for exudative pleural effusion. Pleural effusions associated with pneumonias cause more morbidity and mortality than pleural effusion alone. Retrospective analysis of 472 pleural fluid samples received during the period of January 2010 to December 2011 was done. Organisms and their antibiogram patterns were determined. Among 472 samples 312(66.1%) were culture positive. Organisms isolated were Klebsiella pneumoniae (30%), Pseudomonas aeruginosa (23%), NFGNB (17%), E.coli (15%), Citrobacter (10%), Staphylococcus aureus (5%). K.pneumoniae were sensitive to piperacillin tazobactum (92%) and imipenem (80%), resistant to cefotaxime (90%). Pseudomonas was sensitive to piperacillin tazobactum (73.8%) and amikacin (72%). Bacteriology of pleural infection is changing, Gram negative bacteria from the pleural infections appear to be increasing. The majority of th pleural fluid isolates were hospital pathogens showing high level of resistance to most of the antibiotics. Piperacillin Tazobactum and imipenem were most effective for gram negative isolates.
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