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A REVIEW ON PHARMACEUTICAL GEL

Journal Name:

  • The International Journal of Pharmaceutical Research and Bio-Science

Publication Year:

  • 2012

Key Words:

Author Name
Abstract (2. Language): 
The purpose of writing this review on pharmaceutical gel was to compile the recent literature with special focus on rational approach to topical formulation and basic components of topical drug delivery systems. Topical application of drugs offers potential advantages of delivering the drug directly to the site of action and acting for an extended period of time. Skin is one of the most extensive and readily accessible organs on human body for topical administration and is main route of topical drug delivery system. Gels have better potential as a vehicle to administered drug topically in comparison to ointment, because they are non-sticky requires low energy during the formulation. Topical gels are intended for skin application or to certain mucosal surfaces for local action or percutaneous penetration of medicament or for their emollient or protective action. Gels are evaluated by following parameters such as pH, drug content, viscosity (Brookfield viscometer), spreadability, and extrudability, skin irritation studies, in- vitro release, in-vivo study and stability. Overall, the clinical evidence indicates that topical gel is a safe and effective treatment option for use in the management of skin related diseases.
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  • 5
21-36
  • English

REFERENCES

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Available Online At www.ijprbs.com
Review Article
Santanu Roychowdhury, IJPRBS, 2012; Volume 1(5): 21-36
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ISSN: 2277-8713
IJPRBS
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Available Online At www.ijprbs.com
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ISSN: 2277-8713
IJPRBS
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