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STUDY OF ASSOCIATION BETWEEN SUBCLINICAL HYPOTHYROIDISM AND METABOLIC SYNDROME IN OBESE MIDDLE AGED WOMEN

Journal Name:

  • The International Journal of Pharmaceutical Research and Bio-Science

Publication Year:

  • 2012

Key Words:

Author Name
Abstract (2. Language): 
OBJECTIVES: To study the association of Subclinical Hypothyroidism (SCH) with Metabolic Syndrome (MetS). MATERIAL AND METHODS: Thirty obese women with waist circumference more than 80cms and thirty women as controls were included. Vital data including age, waist circumference and blood pressure were noted for both cases and controls. Cases and control groups were compared in terms of lipid profile parameters including fasting blood glucose, total cholesterol, triglycerides, HDL-Cholesterol, LDL- Cholesterol, VLDL-Cholesterol and Thyroid profile parameters including Thyrotropin (TSH), Triidothyronine (T3), Tetraidothyronine (T4). RESULTS: SCH is known to be associated with increased Blood Pressure, and LDL-Cholesterol, Triglyceride levels and decreased HDL-Cholesterol levels. As expected, the present study found higher levels of Blood pressure, LDL-Cholesterol and Total Triglycerides and lower level of HDL-Cholesterol among test group compared to control group. CONCLUSIONS: We observed that serum TSH levels were higher in obese and they were associated with decreased HDL-C levels and increased triglycerides. Therefore thyroid dysfunction is associated with MetS.
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  • 6
329-340
  • English

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